Impact of omega-3 fatty acids on the gut microbiota

L Costantini, R Molinari, B Farinon… - International journal of …, 2017 - mdpi.com
Long-term dietary habits play a crucial role in creating a host-specific gut microbiota
community in humans. Despite the many publications about the effects of carbohydrates …

[HTML][HTML] All disease begins in the (leaky) gut: role of zonulin-mediated gut permeability in the pathogenesis of some chronic inflammatory diseases

A Fasano - F1000Research, 2020 - ncbi.nlm.nih.gov
Improved hygiene leading to reduced exposure to microorganisms has been implicated as
one possible cause for the recent “epidemic” of chronic inflammatory diseases (CIDs) in …

Obesity, inflammation, and the gut microbiota

AJ Cox, NP West, AW Cripps - The lancet Diabetes & endocrinology, 2015 - thelancet.com
As the prevalence of obesity and associated disease continues to rise and concerns for the
spiralling economic and social costs also escalate, innovative management strategies …

[PDF][PDF] Intestinal microbiota in patients with nonalcoholic fatty liver disease

M Mouzaki, EM Comelli, BM Arendt, J Bonengel… - …, 2013 - Wiley Online Library
Despite evidence that the intestinal microbiota (IM) is involved in the pathogenesis of
obesity, the IM composition of patients with nonalcoholic fatty liver disease (NAFLD) has not …

Zonulin, a regulator of epithelial and endothelial barrier functions, and its involvement in chronic inflammatory diseases

C Sturgeon, A Fasano - Tissue barriers, 2016 - Taylor & Francis
Beside digesting nutrients and absorbing solutes and electrolytes, the intestinal epithelium
with its barrier function is in charge of a tightly controlled antigen trafficking from the …

Gut microbiome, intestinal permeability, and tissue bacteria in metabolic disease: perpetrators or bystanders?

RM Chakaroun, L Massier, P Kovacs - Nutrients, 2020 - mdpi.com
The emerging evidence on the interconnectedness between the gut microbiome and host
metabolism has led to a paradigm shift in the study of metabolic diseases such as obesity …

Gut microbiota-mediated inflammation in obesity: a link with gastrointestinal cancer

PD Cani, BF Jordan - Nature Reviews Gastroenterology & Hepatology, 2018 - nature.com
Overweight and obesity are associated with increased risk of develo** metabolic
disorders such as diabetes and cardiovascular diseases. However, besides these metabolic …

Elevated circulating levels of succinate in human obesity are linked to specific gut microbiota

C Serena, V Ceperuelo-Mallafré, N Keiran… - The ISME …, 2018 - academic.oup.com
Gut microbiota-related metabolites are potential clinical biomarkers for cardiovascular
disease (CVD). Circulating succinate, a metabolite produced by both microbiota and the …

The prenatal gut microbiome: are we colonized with bacteria in utero?

RW Walker, JC Clemente, I Peter, RJF Loos - Pediatric obesity, 2017 - Wiley Online Library
The colonization of the gut with microbes in early life is critical to the develo** newborn
immune system, metabolic function and potentially future health. Maternal microbes are …

Intestinal permeability and its regulation by zonulin: diagnostic and therapeutic implications

A Fasano - Clinical Gastroenterology and Hepatology, 2012 - Elsevier
One of the most important and overlooked functions of the gastrointestinal tract is to provide
a dynamic barrier to tightly controlled antigen trafficking through both the transcellular and …