Thalassemia: impact of consanguineous marriages on most prevalent monogenic disorders of humans

U Saeed, ZZ Piracha - Asian Pacific Journal of Tropical Disease, 2016 - Elsevier
Thalassaemia is an inherited autosomal recessive disorder closely associated with
consanguineous marriages. A literature search was conducted with an aim to investigate …

[HTML][HTML] Global emergence of Langya virus: A serious public health concern

ZZ Piracha, U Saeed, RAI Ahmed… - Journal of Global …, 2023 - ncbi.nlm.nih.gov
Artificial intelligence-mediated rapid diagnostic advances for disease management setups
will aid in lowering the langya viral global burden of disease. be underestimated [7, 8] …

SARS-CoV-2 induced hepatic injuries and liver complications

U Saeed, ZZ Piracha, SR Uppal, Y Waheed… - Frontiers in Cellular …, 2022 - frontiersin.org
Background Coronavirus disease 2019 (COVID-19) is caused by severe acute respiratory
syndrome coronavirus-2 (SARS-CoV-2), which is resilient, highly pathogenic, and rapidly …

[HTML][HTML] Porcine reproductive and respiratory syndrome virus (PRRSV) up-regulates IL-8 expression through TAK-1/JNK/AP-1 pathways

Y Liu, Y Du, H Wang, L Du, W Feng - Virology, 2017 - Elsevier
The acute phase of respiratory distress caused by porcine reproductive and respiratory
syndrome virus (PRRSV) is likely a consequence of the release of inflammatory cytokines in …

Inhibitory effect of low‐intensity pulsed ultrasound on the expression of lipopolysaccharide‐induced inflammatory factors in U937 cells

X Zhang, B Hu, J Sun, J Li, S Liu… - Journal of Ultrasound in …, 2017 - Wiley Online Library
Objectives Low‐intensity pulsed ultrasound (US) has been reported to promote periodontal
tissue regeneration and reduce inflammation in soft tissues and in bone infectious diseases …

Toll-like Receptor-Mediated Immunomodulation of Th1-Type Response Stimulated by Recombinant Antigen of Type 2 Porcine Reproductive and Respiratory …

R Wahyuningtyas, ML Wu, WB Chung, HC Chaung… - Viruses, 2023 - mdpi.com
PRRSV infects CD163-positive macrophages and skews their polarization toward an M2
phenotype, followed by T-cell inactivation. In our previous study, we found that recombinant …

Polymorphisms in Toll-like receptors 1, 2, 5, and 10 are associated with predisposition to Helicobacter pylori infection

SK Tas, D Kirkik, A Tanoglu, R Kahraman… - European Journal of …, 2020 - journals.lww.com
Objective: Toll-like receptors (TLRs) are significant receptors to the innate immune system
which symbolizes a family of pattern recognition receptors. We aimed to investigate …

[HTML][HTML] Viral outbreaks and communicable health hazards due to devastating floods in Pakistan

U Saeed, ZZ Piracha - World Journal of Virology, 2016 - ncbi.nlm.nih.gov
Pakistan is a develo** country that has a population of 190 million people and faces a
huge burden of viral diseases. Every year during monsoon season heavy rain fall and lack …

Immunoinformatics based designing a multi‐epitope vaccine against pathogenic Chandipura vesiculovirus

D Deb, S Basak, T Kar, U Narsaria… - Journal of Cellular …, 2022 - Wiley Online Library
Chandipura vesiculovirus (CHPV) is a rapidly emerging pathogen responsible for causing
acute encephalitis. Due to its widespread occurrence in Asian and African countries, this has …

A Candidate Multi-Epitope Vaccine Against Pathogenic Chandipura Vesiculovirus Identified using Immunoinformatics.

D Deb, S Basak, T Kar, U Narsaria, F Castiglione… - 2020 - researchsquare.com
Chandipura vesiculovirus (CHPV) is a rapidly emerging pathogen responsible for causing
acute encephalitis. Due to its widespread occurrence in Asian and African countries, this has …