Toxicity of mercury: Molecular evidence

L Yang, Y Zhang, F Wang, Z Luo, S Guo, U Strähle - Chemosphere, 2020 - Elsevier
Minamata disease in Japan and the large-scale poisoning by methylmercury (MeHg) in Iraq
caused wide public concerns about the risk emanating from mercury for human health …

Association between heavy metal exposure and Parkinson's disease: a review of the mechanisms related to oxidative stress

S Pyatha, H Kim, D Lee, K Kim - Antioxidants, 2022 - mdpi.com
Parkinson's disease (PD) is a gradually progressing neurodegenerative condition that is
marked by a loss of motor coordination along with non-motor features. Although the precise …

A review on detection of heavy metal ions in water–an electrochemical approach

MB Gumpu, S Sethuraman, UM Krishnan… - Sensors and actuators B …, 2015 - Elsevier
Most of the metal ions are carcinogens and lead to serious health concerns by producing
free radicals. Hence, fast and accurate detection of metal ions has become a critical issue …

Ferroptosis inhibition by oleic acid mitigates iron-overload-induced injury

J Mann, E Reznik, M Santer, MA Fongheiser… - Cell chemical …, 2024 - cell.com
Iron overload, characterized by accumulation of iron in tissues, induces a multiorgan toxicity
whose mechanisms are not fully understood. Using cultured cell lines, Caenorhabditis …

Metals, oxidative stress and neurodegeneration: a focus on iron, manganese and mercury

M Farina, DS Avila, JBT Da Rocha… - Neurochemistry …, 2013 - Elsevier
Essential metals are crucial for the maintenance of cell homeostasis. Among the 23
elements that have known physiological functions in humans, 12 are metals, including iron …

Protective effect of curcumin against heavy metals-induced liver damage

WR García-Niño, J Pedraza-Chaverrí - Food and chemical toxicology, 2014 - Elsevier
Occupational or environmental exposures to heavy metals produce several adverse health
effects. The common mechanism determining their toxicity and carcinogenicity is the …

[HTML][HTML] Acalypha indica Linn: biogenic synthesis of silver and gold nanoparticles and their cytotoxic effects against MDA-MB-231, human breast cancer cells

C Krishnaraj, P Muthukumaran, R Ramachandran… - Biotechnology …, 2014 - Elsevier
This study reports the in vitro cytotoxic effect of biologically synthesized silver and gold
nanoparticles against MDA-MB-231, human breast cancer cells. Formation of silver and gold …

Ferroptosis as a mechanism of non-ferrous metal toxicity

M Aschner, AV Skalny, AC Martins, AI Sinitskii… - Archives of …, 2022 - Springer
Ferroptosis is a recently discovered form of regulated cell death, implicated in multiple
pathologies. Given that the toxicity elicited by some metals is linked to alterations in iron …

Mercury toxicity and neurodegenerative effects

A Carocci, N Rovito, MS Sinicropi, G Genchi - Reviews of environmental …, 2014 - Springer
Neurodegeneration is a broadly defined term that describes the loss of neuronal structure
and function, and produces disorders known as neurodegenerative diseases. A common …

Neurotoxicity linked to dysfunctional metal ion homeostasis and xenobiotic metal exposure: redox signaling and oxidative stress

C Garza-Lombó, Y Posadas, L Quintanar… - Antioxidants & redox …, 2018 - liebertpub.com
Significance: Essential metals such as copper, iron, manganese, and zinc play a role as
cofactors in the activity of a wide range of processes involved in cellular homeostasis and …