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A synopsis of modern-day colorectal cancer: Where we stand
Colorectal cancer (CRC) is a malignancy in the gastro-intestinal (GI) tract which has very
limited treatment options still, despite the vast amount of research undertaken. CRC was first …
limited treatment options still, despite the vast amount of research undertaken. CRC was first …
[HTML][HTML] A review of ULK1-mediated autophagy in drug resistance of cancer
L Liu, L Yan, N Liao, WQ Wu, JL Shi - Cancers, 2020 - mdpi.com
The difficulty of early diagnosis and the development of drug resistance are two major
barriers to the successful treatment of cancer. Autophagy plays a crucial role in several …
barriers to the successful treatment of cancer. Autophagy plays a crucial role in several …
MiR-103a-3p promotes tumour glycolysis in colorectal cancer via hippo/YAP1/HIF1A axis
Z Sun, Q Zhang, W Yuan, X Li, C Chen, Y Guo… - Journal of Experimental …, 2020 - Springer
Background Glycolysis plays an essential role in the growth and metastasis of solid cancer
and has received increasing attention in recent years. However, the complex regulatory …
and has received increasing attention in recent years. However, the complex regulatory …
Lactobacillus plantarum Metabolites Elicit Anticancer Effects by Inhibiting Autophagy-Related Responses
S Jeong, Y Kim, S Park, D Lee, J Lee, SP Hlaing… - Molecules, 2023 - mdpi.com
Lactobacillus plantarum (L. plantarum) is a probiotic that has emerged as novel therapeutic
agents for managing various diseases, such as cancer, atopic dermatitis, inflammatory …
agents for managing various diseases, such as cancer, atopic dermatitis, inflammatory …
Biomarkers for precision immunotherapy in the metastatic setting: hope or reality?
Precision immunotherapy is a crucial approach to improve the efficacy of anti-cancer
treatments, particularly in the metastatic setting. In this respect, accurate patient selection …
treatments, particularly in the metastatic setting. In this respect, accurate patient selection …
Intestinal epithelial SNAI1 promotes the occurrence of colorectal cancer by enhancing EMT and Wnt/β-catenin signaling
F Qing, J Xue, L Sui, Q **ao, T **e, Y Chen, J Huang… - Medical Oncology, 2023 - Springer
Colorectal cancer (CRC) is a prevalent cause of cancer and mortality on a global scale.
SNAI1, a member of the zinc finger transcription superfamily, is a significant contributor to …
SNAI1, a member of the zinc finger transcription superfamily, is a significant contributor to …
Landscape of immunotherapy options for colorectal cancer: current knowledge and future perspectives beyond immune checkpoint blockade
Colorectal cancer is the third most prevalent malignancy in Western countries and a major
cause of death despite recent improvements in screening programs and early detection …
cause of death despite recent improvements in screening programs and early detection …
Third-line treatment and beyond in metastatic colorectal cancer: what do we have and what can we expect?
C Ayala-de Miguel, J Jiménez-Castro… - Critical Reviews in …, 2024 - Elsevier
Colorectal cancer remains the third most common cancer worldwide and the second cause
of cancer-related death. Treatment advances and precision oncological medicine for these …
of cancer-related death. Treatment advances and precision oncological medicine for these …
PBK expression predicts favorable survival in colorectal cancer patients
Colorectal cancer (CRC) is one of the most common gastrointestinal cancers worldwide with
high morbidity and mortality rates. The discovery of small molecule anticancer reagents has …
high morbidity and mortality rates. The discovery of small molecule anticancer reagents has …
STAT1 as a potential prognosis marker for poor outcomes of early stage colorectal cancer with microsatellite instability
Proteomic analyses indicate that STAT1 protein (signal transducer and activator of
transcription 1 or transcription factor ISGF-3 components p91/p84) is upregulated in some …
transcription 1 or transcription factor ISGF-3 components p91/p84) is upregulated in some …