Molecular probes, chemosensors, and nanosensors for optical detection of biorelevant molecules and ions in aqueous media and biofluids

J Krämer, R Kang, LM Grimm, L De Cola… - Chemical …, 2022 - ACS Publications
Synthetic molecular probes, chemosensors, and nanosensors used in combination with
innovative assay protocols hold great potential for the development of robust, low-cost, and …

The multifaceted contributions of mitochondria to cellular metabolism

JB Spinelli, MC Haigis - Nature cell biology, 2018 - nature.com
Although classically appreciated for their role as the powerhouse of the cell, the metabolic
functions of mitochondria reach far beyond bioenergetics. In this Review, we discuss how …

Visible-to-NIR-light activated release: from small molecules to nanomaterials

R Weinstain, T Slanina, D Kand, P Klan - Chemical reviews, 2020 - ACS Publications
Photoactivatable (alternatively, photoremovable, photoreleasable, or photocleavable)
protecting groups (PPGs), also known as caged or photocaged compounds, are used to …

Anti‐inflammatory hydrogel dressings and skin wound healing

C Huang, L Dong, B Zhao, Y Lu… - Clinical and …, 2022 - Wiley Online Library
Hydrogels are promising and widely utilized in the biomedical field. In recent years, the anti‐
inflammatory function of hydrogel dressings has been significantly improved, addressing …

Chemical Biology of H2S Signaling through Persulfidation

MR Filipovic, J Zivanovic, B Alvarez… - Chemical …, 2018 - ACS Publications
Signaling by H2S is proposed to occur via persulfidation, a posttranslational modification of
cysteine residues (RSH) to persulfides (RSSH). Persulfidation provides a framework for …

Resolution of inflammation: a new therapeutic frontier

JN Fullerton, DW Gilroy - Nature reviews Drug discovery, 2016 - nature.com
Dysregulated inflammation is a central pathological process in diverse disease states.
Traditionally, therapeutic approaches have sought to modulate the pro-or anti-inflammatory …

Physiological roles of hydrogen sulfide in mammalian cells, tissues, and organs

G Cirino, C Szabo… - Physiological …, 2023 - journals.physiology.org
Over the last two decades, hydrogen sulfide (H2S) has emerged as an endogenous
regulator of a broad range of physiological functions. H2S belongs to the class of molecules …

A hydrogen sulphide-responsive and depleting nanoplatform for cancer photodynamic therapy

Y Zhang, J Fang, S Ye, Y Zhao, A Wang, Q Mao… - Nature …, 2022 - nature.com
Hydrogen sulfide (H2S) as an important biological gasotransmitter plays a pivotal role in
many physiological and pathological processes. The sensitive and quantitative detection of …

Selective persulfide detection reveals evolutionarily conserved antiaging effects of S-sulfhydration

J Zivanovic, E Kouroussis, JB Kohl, B Adhikari… - Cell metabolism, 2019 - cell.com
Life on Earth emerged in a hydrogen sulfide (H 2 S)-rich environment eons ago and with it
protein persulfidation mediated by H 2 S evolved as a signaling mechanism. Protein …

Prospects and challenges in organosulfur chemistry

M Wang, X Jiang - ACS Sustainable Chemistry & Engineering, 2022 - ACS Publications
Sulfur-containing molecules are increasingly crucial in chemistry-related fields and are
widely applied in life science, material science, food science, and pharmaceutical science …