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Digital histopathology by infrared spectroscopic imaging
R Bhargava - Annual Review of Analytical Chemistry, 2023 - annualreviews.org
Infrared (IR) spectroscopic imaging records spatially resolved molecular vibrational spectra,
enabling a comprehensive measurement of the chemical makeup and heterogeneity of …
enabling a comprehensive measurement of the chemical makeup and heterogeneity of …
Infrared spectroscopic imaging: the next generation
R Bhargava - Applied spectroscopy, 2012 - journals.sagepub.com
Infrared (IR) spectroscopic imaging seemingly matured as a technology in the mid-2000s,
with commercially successful instrumentation and reports in numerous applications. Recent …
with commercially successful instrumentation and reports in numerous applications. Recent …
Using Fourier transform IR spectroscopy to analyze biological materials
IR spectroscopy is an excellent method for biological analyses. It enables the
nonperturbative, label-free extraction of biochemical information and images toward …
nonperturbative, label-free extraction of biochemical information and images toward …
Emerging themes in image informatics and molecular analysis for digital pathology
Pathology is essential for research in disease and development, as well as for clinical
decision making. For more than 100 years, pathology practice has involved analyzing …
decision making. For more than 100 years, pathology practice has involved analyzing …
Infrared spectroscopic imaging advances as an analytical technology for biomedical sciences
Optical chemical imaging seeks to nondestructively acquire spatially resolved chemical
information without the use of labels or probes. The combination of vibrational mid-infrared …
information without the use of labels or probes. The combination of vibrational mid-infrared …
Quantifying collagen structure in breast biopsies using second-harmonic generation imaging
Quantitative second-harmonic generation imaging is employed to assess stromal collagen
in normal, hyperplastic, dysplastic, and malignant breast tissues. The cellular scale …
in normal, hyperplastic, dysplastic, and malignant breast tissues. The cellular scale …
Multimodal chemical analysis of the brain by high mass resolution mass spectrometry and infrared spectroscopic imaging
The brain functions through chemical interactions between many different cell types,
including neurons and glia. Acquiring comprehensive information on complex …
including neurons and glia. Acquiring comprehensive information on complex …
Nuclear architecture analysis of prostate cancer via convolutional neural networks
In this paper, we present an approach of convolutional neural networks (CNNs) to identify
prostate cancers. Prostate tissue specimen samples were obtained from the tissue …
prostate cancers. Prostate tissue specimen samples were obtained from the tissue …
Multiview boosting digital pathology analysis of prostate cancer
Abstract Background and Objective Various digital pathology tools have been developed to
aid in analyzing tissues and improving cancer pathology. The multi-resolution nature of …
aid in analyzing tissues and improving cancer pathology. The multi-resolution nature of …
Improving prediction of prostate cancer recurrence using chemical imaging
Precise Outcome prediction is crucial to providing optimal cancer care across the spectrum
of solid cancers. Clinically-useful tools to predict risk of adverse events (metastases …
of solid cancers. Clinically-useful tools to predict risk of adverse events (metastases …