Curcumin: the Indian solid gold

BB Aggarwal, C Sundaram, N Malani… - The molecular targets and …, 2007 - Springer
Turmeric, derived from the plant Curcuma longa, is a gold-colored spice commonly used in
the Indian subcontinent, not only for health care but also for the preservation of food and as …

Biological properties of curcumin-cellular and molecular mechanisms of action

B Joe, M Vijaykumar, BR Lokesh - Critical reviews in food science …, 2004 - Taylor & Francis
Curcuminoids, a group of phenolic compounds isolated from the roots of Curcuma longa
(Zingiberaceae), exhibit a variety of beneficial effects on health and on events that help in …

Antioxidant role of glutathione S-transferases: 4-Hydroxynonenal, a key molecule in stress-mediated signaling

SS Singhal, SP Singh, P Singhal, D Horne… - Toxicology and applied …, 2015 - Elsevier
Hydroxy-2-trans-nonenal (4HNE), one of the major end products of lipid peroxidation (LPO),
has been shown to induce apoptosis in a variety of cell lines. It appears to modulate …

Application of the hard and soft, acids and bases (HSAB) theory to toxicant–target interactions

RM LoPachin, T Gavin, A DeCaprio… - Chemical research in …, 2012 - ACS Publications
Many chemical toxicants and/or their active metabolites are electrophiles that cause cell
injury by forming covalent bonds with nucleophilic targets on biological macromolecules …

Neuroprotective properties of the natural phenolic antioxidants curcumin and naringenin but not quercetin and fisetin in a 6-OHDA model of Parkinson's disease

V Zbarsky, KP Datla, S Parkar, DK Rai… - Free radical …, 2005 - Taylor & Francis
Although the cause of dopaminergic cell death in Parkinson's disease (PD) remains
unknown, oxidative stress has been strongly implicated. Because of their ability to combat …

Anticancer and carcinogenic properties of curcumin: considerations for its clinical development as a cancer chemopreventive and chemotherapeutic agent

M López‐Lázaro - Molecular nutrition & food research, 2008 - Wiley Online Library
A growing body of research suggests that curcumin, the major active constituent of the
dietary spice turmeric, has potential for the prevention and therapy of cancer. Preclinical …

[CARTE][B] Turmeric: the genus Curcuma

PN Ravindran, KN Babu, K Sivaraman - 2007 - taylorfrancis.com
For the last 6000 years turmeric has been used in Ayurvedic medicine to alleviate pain,
balance digestion, purify body and mind, clear skin diseases, expel phlegm, and invigorate …

Redox regulation in the lens

MF Lou - Progress in retinal and eye research, 2003 - Elsevier
The high content of glutathione (GSH) in the lens is believed to protect thiols in structural
proteins and enzymes for proper biological functions. The lens has both biosynthetic and …

Oxidative stress in asthma: Part of the puzzle

UM Sahiner, E Birben, S Erzurum… - Pediatric Allergy and …, 2018 - Wiley Online Library
An imbalance between the production of reactive oxygen species and the capacity of
antioxidant defense mechanisms favoring oxidants is called oxidative stress and is …

Oral administration of a turmeric extract inhibits LDL oxidation and has hypocholesterolemic effects in rabbits with experimental atherosclerosis

MC Ramırez-Tortosa, MD Mesa, MC Aguilera… - Atherosclerosis, 1999 - Elsevier
The oxidation of low-density lipoproteins (LDL) plays an important role in the development of
atherosclerosis. Curcumin is a yellow pigment obtained from rhizomes of Curcuma longa …