The major goal of this review is a critical discussion of the literature data on asymmetric
synthesis of α-amino acids via Michael addition reactions involving Ni (II)-complexes of …

The asymmetric synthesis of α‐heterofunctionalized α‐and β‐amino acid derivatives has
been a heavily investigated topic over the last years, benefiting from the development of …

Herein, we report an efficient and practical protocol for the asymmetric synthesis of unnatural
α-amino acids (AAs) with γ-tertiary and quaternary carbon centres via selective …

In this work, we report the asymmetric synthesis and characterization of an artificial amino
acid based on triazolyl-thione l-alanine, which was modified with a thiophenyl-substituted …

Four differently substituted chiral Ni (II)‐complexes of dehydroalanine Schiff base were
prepared and reacted with BrCF2COOEt/Cu under the standard reaction conditions. The …

Aliphatic artificial α-amino acids (α-AAs) have attracted great interest in biochemistry and
pharmacy. In this context, we developed a promising practical protocol for the asymmetric …

The selective addition of electrophilic C= C double bonds to the N–H bond of indoles is a
challenging task due to the high nucleophilicity of indoles at their C3‐position. Herein, we …

The conjugate addition of S-, N-and O-heterocyclic nucleophiles to the CC bond of
dehydroalanine, bonded as a Schiff's base to the chiral auxiliary (S)-2-[N-(N′-benzylprolyl) …

The latest discoveries in medicinal chemistry increase day by day with the use of unnatural α-
amino acids. As irreversible enzyme inhibitors non-proteinogenic αamino acids are widely …

By hydrazinolysis of the methyl esters of 3-(4-allyl-3-substituted-5-thioxo-4, 5-dihydro-1H-1,
2, 4-triazol-1-yl) propanoic acids it was established that depending on the reaction …