Arterial spin labeling perfusion of the brain: emerging clinical applications

S Haller, G Zaharchuk, DL Thomas, KO Lovblad… - Radiology, 2016 - pubs.rsna.org
Arterial spin labeling (ASL) is a magnetic resonance (MR) imaging technique used to assess
cerebral blood flow noninvasively by magnetically labeling inflowing blood. In this article, the …

The use of neuroimaging techniques in the early and differential diagnosis of dementia

L Chouliaras, JT O'Brien - Molecular Psychiatry, 2023 - nature.com
Dementia is a leading cause of disability and death worldwide. At present there is no
disease modifying treatment for any of the most common types of dementia such as …

Visual hallucinations in the psychosis spectrum and comparative information from neurodegenerative disorders and eye disease

F Waters, D Collerton, DH Ffytche, R Jardri… - Schizophrenia …, 2014 - academic.oup.com
Much of the research on visual hallucinations (VHs) has been conducted in the context of
eye disease and neurodegenerative conditions, but little is known about these phenomena …

Synaptic proteins predict cognitive decline in Alzheimer's disease and Lewy body dementia

E Bereczki, PT Francis, D Howlett, JB Pereira… - Alzheimer's & …, 2016 - Elsevier
Introduction Our objective was to compare the levels of three synaptic proteins involved in
different steps of the synaptic transmission: Rab3A, SNAP25, and neurogranin, in three …

Neuroimaging biomarkers of neurodegenerative diseases and dementia

SL Risacher, AJ Saykin - Seminars in neurology, 2013 - thieme-connect.com
Neurodegenerative disorders leading to dementia are common diseases that affect many
older and some young adults. Neuroimaging methods are important tools for assessing and …

Imaging blood–brain barrier disruption in neuroinflammation and Alzheimer's disease

RL Lee, KE Funk - Frontiers in Aging Neuroscience, 2023 - frontiersin.org
The blood–brain barrier (BBB) is the neurovascular structure that regulates the passage of
cells and molecules to and from the central nervous system (CNS). Alzheimer's disease (AD) …

Reduced occipital GABA in Parkinson disease with visual hallucinations

MJ Firbank, J Parikh, N Murphy, A Killen, CL Allan… - Neurology, 2018 - AAN Enterprises
Objective To investigate the relationship between visual hallucinations in Parkinson disease
(PD) and levels of γ-aminobutyric acid (GABA) in the primary visual cortex. Methods We …

Dementia with Lewy bodies—from scientific knowledge to clinical insights

NA Arnaoutoglou, JT O'Brien… - Nature Reviews …, 2019 - nature.com
Dementia with Lewy bodies (DLB) is the underlying aetiology of 10–15% of all cases of
dementia and as such is a clinically important diagnosis. In the past few years, substantial …

Grey matter atrophy in prodromal stage of dementia with Lewy bodies and Alzheimer's disease

F Blanc, SJ Colloby, B Cretin, PL de Sousa… - Alzheimer's research & …, 2016 - Springer
Background Little is known about the patterns of brain atrophy in prodromal dementia with
Lewy bodies (pro-DLB). Methods In this study, we used SPM8 with diffeomorphic anatomical …

Neuroimaging characteristics of dementia with Lewy bodies

E Mak, L Su, GB Williams, JT O'Brien - Alzheimer's research & therapy, 2014 - Springer
This review summarises the findings and applications from neuroimaging studies in
dementia with Lewy bodies (DLB), highlighting key differences between DLB and other …