Principles of TAVR valve design, modelling, and testing

OM Rotman, M Bianchi, RP Ghosh… - Expert review of …, 2018 - Taylor & Francis
Introduction: Transcatheter aortic valve replacement (TAVR) has emerged as an effective
minimally-invasive alternative to surgical valve replacement in medium-to high-risk, elderly …

Structural modelling of the cardiovascular system

B Owen, N Bojdo, A Jivkov, B Keavney… - … and modeling in …, 2018 - Springer
Computational modelling of the cardiovascular system offers much promise, but represents
a truly interdisciplinary challenge, requiring knowledge of physiology, mechanics of …

A contact formulation based on a volumetric potential: Application to isogeometric simulations of atrioventricular valves

D Kamensky, F Xu, CH Lee, J Yan, Y Bazilevs… - Computer methods in …, 2018 - Elsevier
This work formulates frictionless contact between solid bodies in terms of a repulsive
potential energy term and illustrates how numerical integration of the resulting forces is …

Results of the interlaboratory computational fluid dynamics study of the FDA benchmark blood pump

SV Ponnaluri, P Hariharan, LH Herbertson… - Annals of Biomedical …, 2023 - Springer
Computational fluid dynamics (CFD) is widely used to simulate blood-contacting medical
devices. To be relied upon to inform high-risk decision making, however, model credibility …

A comprehensive pipeline for multi‐resolution modeling of the mitral valve: V alidation, computational efficiency, and predictive capability

A Drach, AH Khalighi, MS Sacks - International journal for …, 2018 - Wiley Online Library
Multiple studies have demonstrated that the pathological geometries unique to each patient
can affect the durability of mitral valve (MV) repairs. While computational modeling of the MV …

Fluid‐structure interaction of a pulsatile flow with an aortic valve model: a combined experimental and numerical study

J Sigüenza, D Pott, S Mendez… - … journal for numerical …, 2018 - Wiley Online Library
The complex fluid‐structure interaction problem associated with the flow of blood through a
heart valve with flexible leaflets is investigated both experimentally and numerically. In the …

Fluid–structure interaction and structural analyses using a comprehensive mitral valve model with 3D chordal structure

M Toma, DR Einstein, CH Bloodworth IV… - … journal for numerical …, 2017 - Wiley Online Library
Over the years, three‐dimensional models of the mitral valve have generally been organized
around a simplified anatomy. Leaflets have been typically modeled as membranes, tethered …

Error estimates for projection-based dynamic augmented Lagrangian boundary condition enforcement, with application to fluid–structure interaction

Y Yu, D Kamensky, MC Hsu, XY Lu… - … Models and Methods …, 2018 - World Scientific
In this work, we analyze the convergence of the recent numerical method for enforcing fluid–
structure interaction (FSI) kinematic constraints in the immersogeometric framework for …

[HTML][HTML] Modeling risk of coronary obstruction during transcatheter aortic valve replacement

M Heitkemper, H Hatoum, A Azimian, B Yeats… - The Journal of thoracic …, 2020 - Elsevier
Objective In this study we aimed to evaluate risk of coronary obstruction during transcatheter
aortic valve replacement and develop improved criteria based on computational modeling …

Computational methods for fluid-structure interaction simulation of heart valves in patient-specific left heart anatomies

TB Le, M Usta, C Aidun, A Yoganathan, F Sotiropoulos - Fluids, 2022 - mdpi.com
Given the complexity of human left heart anatomy and valvular structures, the fluid–structure
interaction (FSI) simulation of native and prosthetic valves poses a significant challenge for …