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Bacterial antagonism in host-associated microbial communities
L García-Bayona, LE Comstock - Science, 2018 - science.org
BACKGROUND Microbial communities are ubiquitous on Earth. The microbiota of different
habitats are diverse and have distinct functional traits, but there are common ecological …
habitats are diverse and have distinct functional traits, but there are common ecological …
Commensal inter-bacterial interactions sha** the microbiota
The gut microbiota, a complex ecosystem of microorganisms of different kingdoms, impacts
host physiology and disease. Within this ecosystem, inter-bacterial interactions and their …
host physiology and disease. Within this ecosystem, inter-bacterial interactions and their …
The Pseudomonas aeruginosa T6SS delivers a periplasmic toxin that disrupts bacterial cell morphology
The type VI secretion system (T6SS) is crucial in interbacterial competition and is a virulence
determinant of many Gram-negative bacteria. Several T6SS effectors are covalently fused to …
determinant of many Gram-negative bacteria. Several T6SS effectors are covalently fused to …
Polymorphic toxins and their immunity proteins: diversity, evolution, and mechanisms of delivery
All bacteria must compete for growth niches and other limited environmental resources.
These existential battles are waged at several levels, but one common strategy entails the …
These existential battles are waged at several levels, but one common strategy entails the …
Programmed secretion arrest and receptor-triggered toxin export during antibacterial contact-dependent growth inhibition
ZC Ruhe, P Subramanian, K Song, JY Nguyen… - Cell, 2018 - cell.com
Contact-dependent growth inhibition (CDI) entails receptor-mediated delivery of CdiA-
derived toxins into Gram-negative target bacteria. Using electron cryotomography, we show …
derived toxins into Gram-negative target bacteria. Using electron cryotomography, we show …
Phage infection and sub-lethal antibiotic exposure mediate Enterococcus faecalis type VII secretion system dependent inhibition of bystander bacteria
Bacteriophages (phages) are being considered as alternative therapeutics for the treatment
of multidrug resistant bacterial infections. Considering phages have narrow host-ranges, it is …
of multidrug resistant bacterial infections. Considering phages have narrow host-ranges, it is …
Acinetobacter: an emerging pathogen with a versatile secretome
Acinetobacter baumannii is a notorious pathogen that has emerged as a healthcare
nightmare in recent years because it causes serious infections that are associated with high …
nightmare in recent years because it causes serious infections that are associated with high …
Uncovering the Secretion Systems of Acinetobacter baumannii: Structures and Functions in Pathogenicity and Antibiotic Resistance
P Li, S Zhang, J Wang, MM Al-Shamiri, B Han, Y Chen… - Antibiotics, 2023 - mdpi.com
Infections led by Acinetobacter baumannii strains are of great concern in healthcare
environments due to the strong ability of the bacteria to spread through different apparatuses …
environments due to the strong ability of the bacteria to spread through different apparatuses …
Contact-dependent growth inhibition (CDI) systems deploy a large family of polymorphic ionophoric toxins for inter-bacterial competition
TM Halvorsen, KA Schroeder, AM Jones… - PLoS …, 2024 - journals.plos.org
Contact-dependent growth inhibition (CDI) is a widespread form of inter-bacterial
competition mediated by CdiA effector proteins. CdiA is presented on the inhibitor cell …
competition mediated by CdiA effector proteins. CdiA is presented on the inhibitor cell …
Effectiveness of Pseudomonas aeruginosa type VI secretion system relies on toxin potency and type IV pili-dependent interaction
The type VI secretion system (T6SS) is an antibacterial weapon that is used by numerous
Gram-negative bacteria to gain competitive advantage by injecting toxins into adjacent prey …
Gram-negative bacteria to gain competitive advantage by injecting toxins into adjacent prey …