Photolyase: dynamics and electron-transfer mechanisms of DNA repair

M Zhang, L Wang, D Zhong - Archives of biochemistry and biophysics, 2017 - Elsevier
Photolyase, a flavoenzyme containing flavin adenine dinucleotide (FAD) molecule as a
catalytic cofactor, repairs UV-induced DNA damage of cyclobutane pyrimidine dimer (CPD) …

Electron transfer mechanisms of DNA repair by photolyase

D Zhong - Annual review of physical chemistry, 2015 - annualreviews.org
Photolyase is a flavin photoenzyme that repairs two DNA base damage products induced by
ultraviolet (UV) light: cyclobutane pyrimidine dimers and 6-4 photoproducts. With …

Structure of the bifunctional cryptochrome aCRY from Chlamydomonas reinhardtii

S Franz, E Ignatz, S Wenzel, H Zielosko… - Nucleic acids …, 2018 - academic.oup.com
Photolyases and cryptochromes form an almost ubiquitous family of blue light
photoreceptors involved in the repair and maintenance of DNA integrity or regulatory control …

Dynamics and mechanisms of DNA repair by photolyase

Z Liu, L Wang, D Zhong - Physical Chemistry Chemical Physics, 2015 - pubs.rsc.org
Photolyases, a class of flavoproteins, use blue light to repair two types of ultraviolet-induced
DNA damage, a cyclobutane pyrimidine dimer (CPD) and a pyrimidine-pyrimidone (6-4) …

[HTML][HTML] Structural biology of DNA (6-4) photoproducts formed by ultraviolet radiation and interactions with their binding proteins

H Yokoyama, R Mizutani - International journal of molecular sciences, 2014 - mdpi.com
Exposure to the ultraviolet component of sunlight causes DNA damage, which subsequently
leads to mutations, cellular transformation, and cell death. DNA photoproducts with (6-4) …

[HTML][HTML] Avian cryptochrome 4 binds superoxide

J Deviers, F Cailliez, A de la Lande… - Computational and …, 2024 - Elsevier
Flavin-binding cryptochromes are blue-light sensitive photoreceptors that have been
implicated with magnetoreception in some species. The photocycle involves an intra-protein …

Photolyase: Dynamics and mechanisms of repair of sun‐induced DNA damage

M Zhang, L Wang, D Zhong - Photochemistry and photobiology, 2017 - Wiley Online Library
Photolyase, a photomachine discovered half a century ago for repair of sun‐induced DNA
damage of cyclobutane pyrimidine dimers (CPDs) and pyrimidine (6‐4) pyrimidone …

Nonadiabatic QM/MM simulations of fast charge transfer in Escherichia coli DNA photolyase

PB Woiczikowski, T Steinbrecher, T Kubar… - The Journal of …, 2011 - ACS Publications
In this report, we study the photoactivation process in Escherichia coli DNA photolyase,
involving long-range electron transport along a conserved chain of Trp residues between …

Repair of (6‐4) lesions in DNA by (6‐4) photolyase: 20 years of quest for the photoreaction mechanism

J Yamamoto, P Plaza, K Brettel - Photochemistry and …, 2017 - Wiley Online Library
Exposure of DNA to ultraviolet (UV) light from the Sun or from other sources causes the
formation of harmful and carcinogenic crosslinks between adjacent pyrimidine nucleobases …

Formation and direct repair of UV‐induced dimeric DNA pyrimidine lesions

AC Kneuttinger, G Kashiwazaki, S Prill… - Photochemistry and …, 2014 - Wiley Online Library
Direct repair of UV‐induced DNA lesions represents an elegant method for many organisms
to deal with these highly mutagenic and cytotoxic compounds. Although the participating …