Melatonin: a new plant hormone and/or a plant master regulator?

MB Arnao, J Hernández-Ruiz - Trends in Plant Science, 2019 - cell.com
Melatonin is a pleiotropic molecule with many diverse actions in plants. It is considered
primarily an antioxidant with important actions in the control of reactive oxygen and nitrogen …

[HTML][HTML] Protective role of melatonin and its metabolites in skin aging

G Bocheva, RM Slominski, Z Janjetovic, TK Kim… - International journal of …, 2022 - mdpi.com
The skin, being the largest organ in the human body, is exposed to the environment and
suffers from both intrinsic and extrinsic aging factors. The skin aging process is …

Melatonin and phytomelatonin: Chemistry, biosynthesis, metabolism, distribution and bioactivity in plants and animals—An overview

G Mannino, C Pernici, G Serio, C Gentile… - International Journal of …, 2021 - mdpi.com
Melatonin is a ubiquitous indolamine, largely investigated for its key role in the regulation of
several physiological processes in both animals and plants. In the last century, it was …

Association between light at night, melatonin secretion, sleep deprivation, and the internal clock: Health impacts and mechanisms of circadian disruption

Y Touitou, A Reinberg, D Touitou - Life sciences, 2017 - Elsevier
Abstract Exposure to Artificial Light At Night (ALAN) results in a disruption of the circadian
system, which is deleterious to health. In industrialized countries, 75% of the total workforce …

Melatonin as a mitochondria-targeted antioxidant: one of evolution's best ideas

RJ Reiter, S Rosales-Corral, DX Tan, MJ Jou… - Cellular and molecular …, 2017 - Springer
Melatonin is an ancient antioxidant. After its initial development in bacteria, it has been
retained throughout evolution such that it may be or may have been present in every species …

The neurochemistry of autism

R Marotta, MC Risoleo, G Messina, L Parisi… - Brain sciences, 2020 - mdpi.com
Autism spectrum disorder (ASD) refers to complex neurobehavioral and
neurodevelopmental conditions characterized by impaired social interaction and …

Mitochondria: central organelles for melatonin′ s antioxidant and anti-aging actions

RJ Reiter, DX Tan, S Rosales-Corral, A Galano… - Molecules, 2018 - mdpi.com
Melatonin, along with its metabolites, have long been known to significantly reduce the
oxidative stress burden of aging cells or cells exposed to toxins. Oxidative damage is a …

[HTML][HTML] Oxidative stress as a crucial factor in liver diseases

H Cichoż-Lach, A Michalak - World journal of gastroenterology …, 2014 - ncbi.nlm.nih.gov
Redox state constitutes an important background of numerous liver disorders. The redox
state participates in the course of inflammatory, metabolic and proliferative liver diseases …

Melatonin and its metabolites vs oxidative stress: From individual actions to collective protection

A Galano, RJ Reiter - Journal of Pineal Research, 2018 - Wiley Online Library
Oxidative stress (OS) represents a threat to the chemical integrity of biomolecules including
lipids, proteins, and DNA. The associated molecular damage frequently results in serious …

Melatonin: a well‐documented antioxidant with conditional pro‐oxidant actions

HM Zhang, Y Zhang - Journal of pineal research, 2014 - Wiley Online Library
Abstract Melatonin (N‐acetyl‐5‐methoxytryptamine), an indoleamine produced in many
organs including the pineal gland, was initially characterized as a hormone primarily …