This review aims to survey the current state of mechanotransduction in vascular smooth
muscle cells (VSMCs) and endothelial cells (ECs), including their sensing of mechanical …

There have been many recent exciting developments in biomimetic nanoparticles for
biomedical applications. Inflammation, a protective response involving immune cells, blood …

Cardiovascular disease is the leading cause of death worldwide. Although investment in
drug discovery and development has been sky-rocketing, the number of approved drugs has …

The degree of tissue injuries such as the level of scarring or organ dysfunction, and the
immune response against them primarily determine the outcome and speed of healing …

Endothelial cells represent the first biological barrier for compounds, including
nanoparticles, administered via the intravascular route. In the case of ischemic stroke and …

Platelet activation and endothelial damage play essential roles in atherosclerosis. The
pathophysiology of this process is mediated by chemokines and exosomes, two critical …

Although several nanomedicines got clinical approval over the past two decades, the clinical
translation rate is relatively small so far. There are many post-surveillance withdrawals of …

Abstract Intracellular adhesion molecule 1 (ICAM-1) is one of the most extensively studied
inducible cell adhesion molecules which is responsible for several immune functions like T …

Chronic kidney disease (CKD) is one of the major health problems of the modern age. It
represents an important public health challenge with an ever-lasting rising prevalence …

Cancers have always been an intractable problem because of recurrence and drug
resistance. In the past few decades, nanoparticles have been explored intensely to …