Polymeric delivery of therapeutic nucleic acids
The advent of genome editing has transformed the therapeutic landscape for several
debilitating diseases, and the clinical outlook for gene therapeutics has never been more …
debilitating diseases, and the clinical outlook for gene therapeutics has never been more …
Surface modification and endothelialization of biomaterials as potential scaffolds for vascular tissue engineering applications
Surface modification and endothelialization of vascular biomaterials are common
approaches that are used to both resist the nonspecific adhesion of proteins and improve …
approaches that are used to both resist the nonspecific adhesion of proteins and improve …
Cationic polymers and their therapeutic potential
The last decade has witnessed enormous research focused on cationic polymers. Cationic
polymers are the subject of intense research as non-viral gene delivery systems, due to their …
polymers are the subject of intense research as non-viral gene delivery systems, due to their …
Star polymers: Advances in biomedical applications
Over the past decade, star polymers have been widely used in biomedical applications such
as drug delivery, gene delivery, tissue engineering, diagnosis, medical devices, and …
as drug delivery, gene delivery, tissue engineering, diagnosis, medical devices, and …
[HTML][HTML] Current progress in gene delivery technology based on chemical methods and nano-carriers
L **, X Zeng, M Liu, Y Deng, N He - Theranostics, 2014 - ncbi.nlm.nih.gov
Gene transfer methods are promising in the field of gene therapy. Current methods for gene
transfer include three major groups: viral, physical and chemical methods. This review …
transfer include three major groups: viral, physical and chemical methods. This review …
Cyclodextrin-based supramolecular architectures: syntheses, structures, and applications for drug and gene delivery
The supramolecular structures formed between cyclodextrins (CDs) and polymers have
inspired interesting developments of novel supramolecular biomaterials. This review will …
inspired interesting developments of novel supramolecular biomaterials. This review will …
Cyclodextrin-based gene delivery systems
Cyclodextrin (CD) history has been largely dominated by their unique ability to form
inclusion complexes with guests fitting in their hydrophobic cavity. Chemical funcionalization …
inclusion complexes with guests fitting in their hydrophobic cavity. Chemical funcionalization …
Supramolecular cyclodextrin-based drug nanocarriers
Supramolecular systems formed by the binding of several cyclodextrins (CDs) to polymers or
lipids, either via non-covalent or covalent links, open a wide range of possibilities for the …
lipids, either via non-covalent or covalent links, open a wide range of possibilities for the …
Lipid and polymeric carrier-mediated nucleic acid delivery
Importance of the field: Nucleic acids such as plasmid DNA, antisense oligonucleotide, and
RNA interference (RNAi) molecules, have a great potential to be used as therapeutics for the …
RNA interference (RNAi) molecules, have a great potential to be used as therapeutics for the …
Complex macromolecular architecture design via cyclodextrin host/guest complexes
The design of complex macromolecular architectures has driven macromolecular
engineering over the past decades. The introduction of supramolecular chemistry into …
engineering over the past decades. The introduction of supramolecular chemistry into …