Recent advances in cell membrane–camouflaged nanoparticles for cancer phototherapy

X Zhen, P Cheng, K Pu - Small, 2019 - Wiley Online Library
Phototherapy including photothermal therapy (PTT) and photodynamic therapy (PDT)
employs phototherapeutic agents to generate heat or cytotoxic reactive oxygen species …

Platelet-derived drug delivery systems: Pioneering treatment for cancer, cardiovascular diseases, infectious diseases, and beyond

Y Zhu, L Xu, Y Kang, Q Cheng, Y He, X Ji - Biomaterials, 2024 - Elsevier
Platelets play a critical role as circulating cells in the human body and contribute to essential
physiological processes such as blood clotting, hemostasis, vascular repair, and thrombus …

Cancer cells reprogram to metastatic state through the acquisition of platelet mitochondria

W Zhang, H Zhou, H Li, H Mou, E Yinwang, Y Xue… - Cell reports, 2023 - cell.com
Metastasis is the major cause of cancer deaths, and cancer cells evolve to adapt to various
tumor microenvironments, which hinders the treatment of tumor metastasis. Platelets play …

Turbulence activates platelet biogenesis to enable clinical scale ex vivo production

Y Ito, S Nakamura, N Sugimoto, T Shigemori, Y Kato… - Cell, 2018 - cell.com
The ex vivo generation of platelets from human-induced pluripotent cells (hiPSCs) is
expected to compensate donor-dependent transfusion systems. However, manufacturing the …

Evidence-based indications of platelet-rich plasma therapy

S Gupta, A Paliczak, D Delgado - Expert review of hematology, 2021 - Taylor & Francis
Introduction: Platelet-rich plasma (PRP) is an autologous blood-derived product that
contains platelet concentrations at least 2/3 times above the normal level and includes …

Platelet for drug delivery

Y Lu, Q Hu, C Jiang, Z Gu - Current opinion in biotechnology, 2019 - Elsevier
Platelets play a vital physiological role in hemostasis, inflammation and tissue regeneration,
which are associated with wound healing as well as cancer development and metastasis …

Cell cycle–dependent centrosome clustering precedes proplatelet formation

IC Becker, AR Wilkie, E Nikols, E Carminita… - Science …, 2024 - science.org
Platelet-producing megakaryocytes (MKs) primarily reside in the bone marrow, where they
duplicate their DNA content with each cell cycle resulting in polyploid cells with an intricate …

Recent progress in the development of multifunctional nanoplatform for precise tumor phototherapy

J Liu, J Shi, W Nie, S Wang, G Liu… - Advanced healthcare …, 2021 - Wiley Online Library
Phototherapy, including photodynamic therapy and photothermal therapy, mainly relies on
phototherapeutic agents (PAs) to produce heat or toxic reactive oxygen species (ROS) to kill …

[HTML][HTML] Platelet-rich plasma in dermatology: new insights on the cellular mechanism of skin repair and regeneration

CG Manole, C Soare, LC Ceafalan, VM Voiculescu - Life, 2023 - mdpi.com
The skin's recognised functions may undergo physiological alterations due to ageing,
manifesting as varying degrees of facial wrinkles, diminished tautness, density, and volume …

Platelet biogenesis in the lung circulation

E Lefrançais, MR Looney - Physiology, 2019 - journals.physiology.org
Megakaryocytes are normal cellular components of the blood returning to the heart and
entering the lungs, and historical data has pointed to a role of the lungs in platelet …