Primary outcomes and anticipated effect sizes in randomised clinical trials assessing peripheral and truncal nerve blocks: a systematic sco** review

S Sorenson, SSB Flyger, L **el, APH Karlsen… - British Journal of …, 2024 - Elsevier
Background Peripheral and truncal nerve blocks provide effective analgesia facilitating
perioperative care. However, thresholds for clinically relevant effects remain undetermined …

Regional Analgesia in Pediatric Cardiothoracic Surgery: A Bayesian Network Meta-Analysis

Y Ren, L Li, J Gao, L Hua, T Zheng, F Wang… - Journal of Cardiothoracic …, 2025 - Elsevier
Background Various regional analgesia techniques are used to reduce postoperative pain
in pediatric patients undergoing cardiothoracic surgeries. This study aimed to determine the …

Effects of popliteal plexus block after total knee arthroplasty: a randomized clinical trial

JK Sørensen, U Grevstad, P Jaeger… - Regional Anesthesia & …, 2024 - rapm.bmj.com
Background and objectives Motor-sparing peripheral nerve blocks enhance multimodal
opioid-sparing strategies after total knee arthroplasty. We hypothesized that adding a …

Transversus abdominis plane block in minimally invasive colon surgery: a multicenter three-arm randomized controlled superiority and non-inferiority clinical trial

CB Salmonsen, KHW Lange, J Kleif… - Regional Anesthesia & …, 2024 - rapm.bmj.com
Background and objectives The transversus abdominis plane (TAP) block is the most widely
used abdominal field block in colorectal surgery with a postoperative enhanced recovery …

Anterior quadratus lumborum blocks for postoperative pain treatment following intra‐abdominal surgery: A systematic review with meta‐analyses and trial sequential …

K Tanggaard, C Gronlund, MV Nielsen… - Acta …, 2025 - Wiley Online Library
Background The anterior quadratus lumborum (QL) block may be used for postoperative
pain management for intra‐abdominal surgeries, but the evidence is uncertain. We aimed to …

Opioids and personalized analgesia in the perioperative setting: A protocol for five systematic reviews

APH Karlsen, PB Sunde, MH Olsen… - Acta …, 2024 - Wiley Online Library
Background Treatment with opioids is a mainstay in perioperative pain management. While
the leading treatment paradigm has been procedure‐specific pain management, efforts …

Intraoperative opioid administrations, rescue doses in the post‐anaesthesia care unit and clinician‐perceived factors for dose adjustments in adults: A Danish …

TXM Tran, M Wetterslev, AK Nørskov… - Acta …, 2025 - Wiley Online Library
Background The impact of demographic‐and surgical factors on individual perioperative
opioid requirements is not fully understood. Anaesthesia personnel adjust opioid …

Primary outcomes and anticipated effect sizes in randomised clinical trials assessing adjuncts to peripheral nerve blocks: A sco** review

SSB Flyger, S Sorenson, L **el… - Acta …, 2024 - Wiley Online Library
Background Prolonging effects of adjuncts to local anaesthetics in peripheral nerve blocks
have been demonstrated in randomised clinical trials. The chosen primary outcome and …

Popliteal plexus block in total knee arthroplasty: a single-center randomized controlled double-blinded trial

K Stebler, N Elia, I Zaccaria… - Regional Anesthesia & …, 2024 - rapm.bmj.com
Introduction Whether a popliteal plexus block improves postoperative pain following total
knee arthroplasty remains debated. This randomized trial tested if adding a popliteal plexus …

Optimal non-opioid analgesic combinations after total hip arthroplasty

FS Xue, DY Lin, XC Zheng - The Lancet Rheumatology, 2024 - thelancet.com
By conducting a randomised controlled trial, Joakim Steiness and colleagues1 compared
the benefits and adverse events of different nonopioid analgesic combinations as the …