Second harmonic generation microscopy: a powerful tool for bio-imaging

A Aghigh, S Bancelin, M Rivard, M Pinsard… - Biophysical …, 2023 - Springer
Second harmonic generation (SHG) microscopy is an important optical imaging technique in
a variety of applications. This article describes the history and physical principles of SHG …

Nonlinear optical microscopy: From fundamentals to applications in live bioimaging

V Parodi, E Jacchetti, R Osellame, G Cerullo… - … in bioengineering and …, 2020 - frontiersin.org
A recent challenge in the field of bioimaging is to image vital, thick, and complex tissues in
real time and in non-invasive mode. Among the different tools available for diagnostics …

Label-free multiphoton microscopy: much more than fancy images

G Borile, D Sandrin, A Filippi, KI Anderson… - International Journal of …, 2021 - mdpi.com
Multiphoton microscopy has recently passed the milestone of its first 30 years of activity in
biomedical research. The growing interest around this approach has led to a variety of …

[HTML][HTML] Harmonic generation at the nanoscale

L Bonacina, PF Brevet, M Finazzi… - Journal of Applied …, 2020 - pubs.aip.org
Nonlinear photon conversion is a fundamental physical process that lies on the basis of
many modern disciplines, from bioimaging and theranostics in nanomedicine to material …

De Novo Design of Aggregation‐Induced Emission Luminogen for Three‐Photon Fluorescence Imaging of Subcortical Structures Excited at Both NIR‐III and NIR‐IV …

S Tong, W Xu, J Zhong, M Kang, X Chen… - Advanced Functional …, 2023 - Wiley Online Library
Abstract Three‐photon fluorescence (3PF) imaging excited at 1700 nm window is an
enabling technology for visualizing deep brain structures and dynamics. Recently, the 2200 …

Towards next-generation diagnostic pathology: AI-empowered label-free multiphoton microscopy

S Wang, J Pan, X Zhang, Y Li, W Liu, R Lin… - Light: Science & …, 2024 - nature.com
Diagnostic pathology, historically dependent on visual scrutiny by experts, is essential for
disease detection. Advances in digital pathology and developments in computer vision …

PSHG-TISS: A collection of polarization-resolved second harmonic generation microscopy images of fixed tissues

R Hristu, SG Stanciu, A Dumitru, LG Eftimie, B Paun… - Scientific Data, 2022 - nature.com
Second harmonic generation (SHG) microscopy is acknowledged as an established
imaging technique capable to provide information on the collagen architecture in tissues that …

Nano-positioning and tubulin conformation contribute to axonal transport regulation of mitochondria along microtubules

V Van Steenbergen… - Proceedings of the …, 2022 - National Acad Sciences
Correct spatiotemporal distribution of organelles and vesicles is crucial for healthy cell
functioning and is regulated by intracellular transport mechanisms. Controlled transport of …

Influence of hematoxylin and eosin staining on the quantitative analysis of second harmonic generation imaging of fixed tissue sections

R Hristu, SG Stanciu, A Dumitru, B Paun… - Biomedical Optics …, 2021 - opg.optica.org
Second harmonic generation (SHG) microscopy has emerged over the past two decades as
a powerful tool for tissue characterization and diagnostics. Its main applications in medicine …

Effect of out of plane orientation on polarization second harmonic generation of single collagen fibrils

MA Harvey, R Cisek, D Tokarz… - Biomedical Optics Express, 2023 - opg.optica.org
Second harmonic generation (SHG) microscopy has emerged as a powerful technique for
visualizing collagen organization within tissues. Amongst the many advantages of SHG is its …