3D printing in personalized drug delivery: An overview of hot-melt extrusion-based fused deposition modeling

N Dumpa, A Butreddy, H Wang, N Komanduri… - International journal of …, 2021 - Elsevier
Advancements in pharmaceutical technologies have led to the personalization of therapies
over the last decade. Three-dimensional printing (3DP) is an emerging technique in the …

Coupling hot melt extrusion and fused deposition modeling: Critical properties for successful performance

S Bandari, D Nyavanandi, N Dumpa… - Advanced drug delivery …, 2021 - Elsevier
Interest in 3D printing for pharmaceutical applications has increased in recent years.
Compared to other 3D printing techniques, hot melt extrusion (HME)-based fused deposition …

Shape memory materials and 4D printing in pharmaceutics

A Melocchi, M Uboldi, M Cerea, A Foppoli… - Advanced Drug Delivery …, 2021 - Elsevier
Shape memory materials (SMMs), including alloys and polymers, can be programmed into a
temporary configuration and then recover the original shape in which they were processed …

[HTML][HTML] Polymer selection for hot-melt extrusion coupled to fused deposition modelling in pharmaceutics

GG Pereira, S Figueiredo, AI Fernandes, JF Pinto - Pharmaceutics, 2020 - mdpi.com
Three-dimensional (3D) printing offers the greatest potential to revolutionize the future of
pharmaceutical manufacturing by overcoming challenges of conventional pharmaceutical …

Hot-melt extrusion: from theory to application in pharmaceutical formulation—where are we now?

H Patil, SK Vemula, S Narala, P Lakkala… - AAPS …, 2024 - Springer
Hot-melt extrusion (HME) is a globally recognized, robust, effective technology that
enhances the bioavailability of poorly soluble active pharmaceutical ingredients and offers …

Hot-melt extrusion: Highlighting recent advances in pharmaceutical applications

S Tambe, D Jain, Y Agarwal, P Amin - Journal of Drug Delivery Science …, 2021 - Elsevier
Hot-melt extrusion (HME) has emerged as a pioneering manufacturing technology for
pharmaceutical industries, and the utilization is overgrowing due to its unit operation, cost …

3D printing by fused deposition modeling of single-and multi-compartment hollow systems for oral delivery–A review

A Melocchi, M Uboldi, A Maroni, A Foppoli… - International journal of …, 2020 - Elsevier
Feasibility of fused deposition modeling in 3D printing of hollow systems intended to convey
different formulations for oral administration has recently been investigated. A major …

Hypromellose acetate succinate based amorphous solid dispersions via hot melt extrusion: Effect of drug physicochemical properties

S Sarabu, VR Kallakunta, S Bandari, A Batra, V Bi… - Carbohydrate …, 2020 - Elsevier
In this study, the impact of drug and hydroxypropyl methylcellulose acetate succinate
(HPMCAS) grades physicochemical properties on extrusion process, dissolution and …

Quality-by-design in hot melt extrusion based amorphous solid dispersions: An industrial perspective on product development

A Butreddy, S Bandari, MA Repka - European Journal of Pharmaceutical …, 2021 - Elsevier
An industrially feasible approach to overcome the solubility and bioavailability limitations of
poorly soluble active pharmaceutical ingredients is the development of amorphous solid …

A review of hot melt extrusion technology: advantages, applications, key factors and future prospects

X Li, X Hong, S Shuai, X Han, C Li, H Zhang… - Journal of Drug Delivery …, 2024 - Elsevier
After decades of development, hot melt extrusion (HME) technology has matured as a well-
established pharmaceutical methodology. Through the process of extruding both drug and …