Metabolomics 20 years on: what have we learned and what hurdles remain?
The term metabolome was coined in 1998, by analogy to genome, transcriptome and
proteome. The first research papers using the terms metabolomics, metabonomics …
proteome. The first research papers using the terms metabolomics, metabonomics …
Metabolomics for functional genomics, systems biology, and biotechnology
Metabolomics now plays a significant role in fundamental plant biology and applied
biotechnology. Plants collectively produce a huge array of chemicals, far more than are …
biotechnology. Plants collectively produce a huge array of chemicals, far more than are …
Gas chromatography mass spectrometry–based metabolite profiling in plants
The concept of metabolite profiling has been around for decades, but technical innovations
are now enabling it to be carried out on a large scale with respect to the number of both …
are now enabling it to be carried out on a large scale with respect to the number of both …
Visualization of GC/TOF-MS-based metabolomics data for identification of biochemically interesting compounds using OPLS class models
S Wiklund, E Johansson, L Sjöström… - Analytical …, 2008 - ACS Publications
Metabolomics studies generate increasingly complex data tables, which are hard to
summarize and visualize without appropriate tools. The use of chemometrics tools, eg …
summarize and visualize without appropriate tools. The use of chemometrics tools, eg …
Metabolomic analysis in food science: a review
Metabolomics has emerged as an important tool in many disciplines such as human
diseases and nutrition, drug discovery, plant physiology and others. In food science …
diseases and nutrition, drug discovery, plant physiology and others. In food science …
Statistical strategies for avoiding false discoveries in metabolomics and related experiments
Many metabolomics, and other high-content or high-throughput, experiments are set up
such that the primary aim is the discovery of biomarker metabolites that can discriminate …
such that the primary aim is the discovery of biomarker metabolites that can discriminate …
Potato glycoalkaloids and metabolites: roles in the plant and in the diet
M Friedman - Journal of agricultural and food chemistry, 2006 - ACS Publications
Potatoes, members of the Solanaceae plant family, serve as major, inexpensive low-fat food
sources providing energy (starch), high-quality protein, fiber, and vitamins. Potatoes also …
sources providing energy (starch), high-quality protein, fiber, and vitamins. Potatoes also …
Foodomics: MS‐based strategies in modern food science and nutrition
M Herrero, C Simó, V García‐Cañas… - Mass spectrometry …, 2012 - Wiley Online Library
Modern research in food science and nutrition is moving from classical methodologies to
advanced analytical strategies in which MS‐based techniques play a crucial role. In this …
advanced analytical strategies in which MS‐based techniques play a crucial role. In this …
Current metabolomics: practical applications
The field of metabolomics continues to grow rapidly over the last decade and has been
proven to be a powerful technology in predicting and explaining complex phenotypes in …
proven to be a powerful technology in predicting and explaining complex phenotypes in …
Plant metabolomics: from holistic hope, to hype, to hot topic
RD Hall - New phytologist, 2006 - Wiley Online Library
In a short time, plant metabolomics has gone from being just an ambitious concept to being
a rapidly growing, valuable technology applied in the stride to gain a more global picture of …
a rapidly growing, valuable technology applied in the stride to gain a more global picture of …