Integrons have played a major role in the rise and spread of multidrug resistance in Gram-
negative pathogens and are nowadays commonplace among clinical isolates. These …

Integrons are key elements in the rise and spread of multidrug resistance in Gram-negative
bacteria. These genetic platforms capture cassettes containing promoterless genes and …

Integrons are genetic platforms that acquire new genes encoded in integron cassettes (ICs),
building arrays of adaptive functions. ICs generally encode promoterless genes, whose …

Integrons are genetic elements that increase the evolvability of bacteria by capturing new
genes and stockpiling them in arrays. Sedentary chromosomal integrons (SCIs) can be …

Integrons are bacterial genetic elements that capture, stockpile and modulate the expression
of genes encoded in integron cassettes. Mobile Integrons (MI) are borne on plasmids, acting …

By capturing and expressing exogenous resistance gene cassettes through site-specific
recombination, integrons play important roles in the horizontal transfer of antimicrobial …

Integrons are genetic elements that increase the evolvability of bacteria by capturing new
genes and stockpiling them in arrays. Sedentary chromosomal integrons (SCIs) can be …

Pharmacology of antimicrobial drugs comprises pharmacodynamics (PD) and
pharmacokinetics (PK). PD refers to studying drugs' mode of action at different …

Bacteria must face and adapt to a variety of physicochemical conditions in the environment
and during infection. A key condition is the partial pressure of oxygen (PO2), since many …

Integrons are genetic platforms that acquire new genes encoded in integron cassettes (ICs),
building arrays of adaptive functions. ICs generally encode promoterless genes, whose …