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Fluorescent probes for disease diagnosis
The identification and detection of disease-related biomarkers is essential for early clinical
diagnosis, evaluating disease progression, and for the development of therapeutics …
diagnosis, evaluating disease progression, and for the development of therapeutics …
The role of BCL-2 family proteins in regulating apoptosis and cancer therapy
S Qian, Z Wei, W Yang, J Huang, Y Yang… - Frontiers in …, 2022 - frontiersin.org
Apoptosis, as a very important biological process, is a response to developmental cues or
cellular stress. Impaired apoptosis plays a central role in the development of cancer and …
cellular stress. Impaired apoptosis plays a central role in the development of cancer and …
Molecular pathogenesis and systemic therapies for hepatocellular carcinoma
Hepatocellular carcinoma (HCC) remains one of the most prevalent and deadliest cancers.
The poor outcome associated with HCC is dramatically changing due to the advent of …
The poor outcome associated with HCC is dramatically changing due to the advent of …
Tumor‐associated macrophages in liver cancer: from mechanisms to therapy
K Cheng, N Cai, J Zhu, X Yang, H Liang… - Cancer …, 2022 - Wiley Online Library
Multidimensional analyses have demonstrated the presence of a unique tumor
microenvironment (TME) in liver cancer. Tumor‐associated macrophages (TAMs) are …
microenvironment (TME) in liver cancer. Tumor‐associated macrophages (TAMs) are …
The immunological and metabolic landscape in primary and metastatic liver cancer
The liver is the sixth most common site of primary cancer in humans, and generally arises in
a background of cirrhosis and inflammation. Moreover, the liver is frequently colonized by …
a background of cirrhosis and inflammation. Moreover, the liver is frequently colonized by …
Cholangiocarcinoma 2020: the next horizon in mechanisms and management
Cholangiocarcinoma (CCA) includes a cluster of highly heterogeneous biliary malignant
tumours that can arise at any point of the biliary tree. Their incidence is increasing globally …
tumours that can arise at any point of the biliary tree. Their incidence is increasing globally …
Emerging roles and the regulation of aerobic glycolysis in hepatocellular carcinoma
J Feng, J Li, L Wu, Q Yu, J Ji, J Wu, W Dai… - Journal of Experimental & …, 2020 - Springer
Liver cancer has become the sixth most diagnosed cancer and the fourth leading cause of
cancer death worldwide. Hepatocellular carcinoma (HCC) is responsible for up to 75–85 …
cancer death worldwide. Hepatocellular carcinoma (HCC) is responsible for up to 75–85 …
Tumour evolution in hepatocellular carcinoma
Hepatocellular carcinoma (HCC), the most common form of primary liver cancer, typically
develops on the background of chronic liver disease and is an aggressive disease with …
develops on the background of chronic liver disease and is an aggressive disease with …
Comprehensive analysis of spatial architecture in primary liver cancer
Heterogeneity is the major challenge for cancer prevention and therapy. Here, we first
constructed high-resolution spatial transcriptomes of primary liver cancers (PLCs) containing …
constructed high-resolution spatial transcriptomes of primary liver cancers (PLCs) containing …
Neoantigen: a new breakthrough in tumor immunotherapy
Z Zhang, M Lu, Y Qin, W Gao, L Tao, W Su… - Frontiers in …, 2021 - frontiersin.org
Cancer immunotherapy works by stimulating and strengthening the body's anti-tumor
immune response to eliminate cancer cells. Over the past few decades, immunotherapy has …
immune response to eliminate cancer cells. Over the past few decades, immunotherapy has …