Transition-metal-based nanozymes: synthesis, mechanisms of therapeutic action, and applications in cancer treatment

Q Fu, C Wei, M Wang - ACS nano, 2024 - ACS Publications
Cancer, as one of the leading causes of death worldwide, drives the advancement of cutting-
edge technologies for cancer treatment. Transition-metal-based nanozymes emerge as …

Deep insight of design, mechanism, and cancer theranostic strategy of nanozymes

L Yang, S Dong, S Gai, D Yang, H Ding, L Feng… - Nano-Micro Letters, 2024 - Springer
Since the discovery of enzyme-like activity of Fe3O4 nanoparticles in 2007, nanozymes are
becoming the promising substitutes for natural enzymes due to their advantages of high …

A photo-triggered self-accelerated nanoplatform for multifunctional image-guided combination cancer immunotherapy

X Kang, Y Zhang, J Song, L Wang, W Li, J Qi… - Nature …, 2023 - nature.com
Precise and efficient image-guided immunotherapy holds great promise for cancer
treatment. Here, we report a self-accelerated nanoplatform combining an aggregation …

Single atom catalysts remodel tumor microenvironment for augmented sonodynamic immunotherapy

B Geng, J Hu, X He, Z Zhang, J Cai, D Pan… - Advanced …, 2024 - Wiley Online Library
The immunosuppressive tumor microenvironment (TME) is a huge hurdle in immunotherapy.
Sono‐immunotherapy is a new treatment modality that can reverse immunosuppressive …

Reactive Oxygen Species‐Scavenging Nanosystems in the Treatment of Diabetic Wounds

Y **ong, X Chu, T Yu, S Knoedler… - Advanced …, 2023 - Wiley Online Library
Diabetic wounds are characterized by drug‐resistant bacterial infections, biofilm formation,
impaired angiogenesis and perfusion, and oxidative damage to the microenvironment …

Molecularly engineered room-temperature phosphorescence for biomedical application: from the visible toward second near-infrared window

B Chang, J Chen, J Bao, T Sun, Z Cheng - Chemical Reviews, 2023 - ACS Publications
Phosphorescence, characterized by luminescent lifetimes significantly longer than that of
biological autofluorescence under ambient environment, is of great value for biomedical …

Orchestrated copper-based nanoreactor for remodeling tumor microenvironment to amplify cuproptosis-mediated anti-tumor immunity in colorectal cancer

XK **, JL Liang, SM Zhang, QX Huang, SK Zhang… - Materials Today, 2023 - Elsevier
Owing to the deficiency of infiltrating immune cells and the accumulation of
immunosuppressive cells in tumor microenvironment (TME), immunotherapy remains …

Architecture of Vanadium‐Based MXene Dysregulating Tumor Redox Homeostasis for Amplified Nanozyme Catalytic/Photothermal Therapy

R Zhao, Y Zhu, L Feng, B Liu, Y Hu, H Zhu… - Advanced …, 2024 - Wiley Online Library
Taking the significance of the special microenvironment for tumor cell survival into account,
disrupting tumor redox homeostasis is highly prospective for improving therapeutic efficacy …

Nanomaterials for photothermal cancer therapy

S Duan, Y Hu, Y Zhao, K Tang, Z Zhang, Z Liu… - RSC …, 2023 - pubs.rsc.org
Cancer has emerged as a pressing global public health issue, and improving the
effectiveness of cancer treatment remains one of the foremost challenges of modern …

A noble AuPtAg‐GOx nanozyme for synergistic tumor immunotherapy induced by starvation therapy‐augmented mild photothermal therapy

M Wang, M Chang, P Zheng, Q Sun, G Wang… - Advanced …, 2022 - Wiley Online Library
Notwithstanding immune checkpoint blocking (ICB) therapy has made eminent clinical
breakthroughs, overcoming immunologically “cold” tumors remains challenging. Here, a …