Questioning the fetal microbiome illustrates pitfalls of low-biomass microbial studies

KM Kennedy, MC de Goffau, ME Perez-Muñoz… - Nature, 2023 - nature.com
Whether the human fetus and the prenatal intrauterine environment (amniotic fluid and
placenta) are stably colonized by microbial communities in a healthy pregnancy remains a …

The role of the microbiota in periodontal disease

MA Curtis, PI Diaz, TE Van Dyke - Periodontology 2000, 2020 - Wiley Online Library
The last decade has witnessed unparalleled advances in our understanding of the
complexity of the oral microbiome and the compositional changes that occur in subgingival …

The association between microplastics and microbiota in placentas and meconium: the first evidence in humans

S Liu, X Liu, J Guo, R Yang, H Wang… - … science & technology, 2022 - ACS Publications
Pregnancy and infancy are vulnerable times for detrimental environmental exposures.
However, the exposure situation of microplastics (MPs) for mother–infant pairs and the …

The first microbial colonizers of the human gut: composition, activities, and health implications of the infant gut microbiota

C Milani, S Duranti, F Bottacini, E Casey… - Microbiology and …, 2017 - Am Soc Microbiol
The human gut microbiota is engaged in multiple interactions affecting host health during
the host's entire life span. Microbes colonize the neonatal gut immediately following birth …

Beneficial effects of dietary polyphenols on gut microbiota and strategies to improve delivery efficiency

A Kumar Singh, C Cabral, R Kumar, R Ganguly… - Nutrients, 2019 - mdpi.com
The human intestine contains an intricate ecological community of dwelling bacteria,
referred as gut microbiota (GM), which plays a pivotal role in host homeostasis. Multiple …

A critical assessment of the “sterile womb” and “in utero colonization” hypotheses: implications for research on the pioneer infant microbiome

ME Perez-Muñoz, MC Arrieta, AE Ramer-Tait, J Walter - microbiome, 2017 - Springer
After more than a century of active research, the notion that the human fetal environment is
sterile and that the neonate's microbiome is acquired during and after birth was an accepted …

Development of the gut microbiota in infancy and its impact on health in later life

M Tanaka, J Nakayama - Allergology International, 2017 - jstage.jst.go.jp
abstract Gut microbial ecology and function are dynamic in infancy, but are stabilized in
childhood. The 'new friends' have a great impact on the development of the digestive tract …

[HTML][HTML] Factors affecting the composition of the gut microbiota, and its modulation

N Hasan, H Yang - PeerJ, 2019 - peerj.com
Gut microbiota have important functions in the body, and imbalances in the composition and
diversity of those microbiota can cause several diseases. The host fosters favorable …

Maturation of the infant microbiome community structure and function across multiple body sites and in relation to mode of delivery

DM Chu, J Ma, AL Prince, KM Antony, MD Seferovic… - Nature medicine, 2017 - nature.com
Human microbial communities are characterized by their taxonomic, metagenomic and
metabolic diversity, which varies by distinct body sites and influences human physiology …

The microbiome in early life: implications for health outcomes

S Tamburini, N Shen, HC Wu, JC Clemente - Nature medicine, 2016 - nature.com
Recent studies have characterized how host genetics, prenatal environment and delivery
mode can shape the newborn microbiome at birth. Following this, postnatal factors, such as …