Comprehensive management of cardiovascular risk factors for adults with type 2 diabetes: a scientific statement from the American Heart Association

JJ Joseph, P Deedwania, T Acharya, D Aguilar… - Circulation, 2022 - Am Heart Assoc
Cardiovascular disease remains the leading cause of death in patients with diabetes.
Cardiovascular disease in diabetes is multifactorial, and control of the cardiovascular risk …

2019 ESC/EAS Guidelines for the management of dyslipidaemias: lipid modification to reduce cardiovascular risk The Task Force for the management of …

F Mach, C Baigent, AL Catapano… - European heart …, 2020 - academic.oup.com
version of the Guidelines, which is freely available via the ESC and EAS websites and
hosted on their journals' websites (EHJ and Atherosclerosis Journal). The National Cardiac …

HDL and reverse cholesterol transport: Basic mechanisms and their roles in vascular health and disease

M Ouimet, TJ Barrett, EA Fisher - Circulation research, 2019 - Am Heart Assoc
Cardiovascular disease, with atherosclerosis as the major underlying factor, remains the
leading cause of death worldwide. It is well established that cholesterol ester-enriched foam …

Extreme high high-density lipoprotein cholesterol is paradoxically associated with high mortality in men and women: two prospective cohort studies

CM Madsen, A Varbo… - European heart …, 2017 - academic.oup.com
Aims High-density lipoprotein (HDL) cholesterol concentrations are inversely associated
with cardiovascular disease and mortality across a range of concentrations, but genetic …

Genetic drug target validation using Mendelian randomisation

AF Schmidt, C Finan, M Gordillo-Marañón… - Nature …, 2020 - nature.com
Mendelian randomisation (MR) analysis is an important tool to elucidate the causal
relevance of environmental and biological risk factors for disease. However, causal …

[HTML][HTML] Best (but oft-forgotten) practices: the design, analysis, and interpretation of Mendelian randomization studies

PC Haycock, S Burgess, KH Wade, J Bowden… - The American journal of …, 2016 - Elsevier
abstract Mendelian randomization (MR) is an increasingly important tool for appraising
causality in observational epidemiology. The technique exploits the principle that genotypes …

Supplemental vitamins and minerals for CVD prevention and treatment

DJA Jenkins, JD Spence, EL Giovannucci, Y Kim… - Journal of the American …, 2018 - jacc.org
The authors identified individual randomized controlled trials from previous meta-analyses
and additional searches, and then performed meta-analyses on cardiovascular disease …

Relationship between gut microbiota and circulating metabolites in population-based cohorts

D Vo**ovic, D Radjabzadeh, A Kurilshikov… - Nature …, 2019 - nature.com
Gut microbiota has been implicated in major diseases affecting the human population and
has also been linked to triglycerides and high-density lipoprotein levels in the circulation …

Risk of cardiomyopathy and cardiac arrhythmias in patients with nonalcoholic fatty liver disease

QM Anstee, A Mantovani, H Tilg… - Nature Reviews …, 2018 - nature.com
Nonalcoholic fatty liver disease (NAFLD) is a common, progressive liver disease that affects
up to one-quarter of the adult population worldwide. The clinical and economic burden of …

Association between plant-based diets and plasma lipids: a systematic review and meta-analysis

Y Yokoyama, SM Levin, ND Barnard - Nutrition reviews, 2017 - academic.oup.com
Context Although a recent meta-analysis of randomized controlled trials showed that
adoption of a vegetarian diet reduces plasma lipids, the association between vegetarian …