Understanding the genetic architecture of athletic performance is an important step in the
development of methods for talent identification in sport. Research concerned with …

The ability to reprogram the transcriptional circuitry by remodeling the three-dimensional
structure of the genome is exploited by cancer cells to promote tumorigenesis. This …

Sports genomics is the scientific discipline that focuses on the organization and function of
the genome in elite athletes, and aims to develop molecular methods for talent identification …

Abstract Thalassemias (α, β, γ, δ, δβ, and εγδβ) are the most common genetic disorders
worldwide and constitute a heterogeneous group of hereditary diseases characterized by …

Deregulation of microRNAs (miRNAs) can drive oncogenesis, tumor progression, and
metastasis by acting cell-autonomously in cancer cells. However, solid tumors are also …

Skeletal myogenesis, like hematopoiesis, occurs in successive developmental stages that
involve different cell populations and expression of different genes. We show here that the …

Epigenetic modifications regulate developmental genes involved in stem cell identity and
lineage choice. NFI-A is a posttranscriptional microRNA-223 (miR-223) target directing …

To investigate the association between multiple single-nucleotide polymorphisms (SNPs),
aerobic performance and elite endurance athlete status in Russians. By using GWAS …

The transcription factor (TF) nuclear factor IX (NFIX) is a positive regulator of hematopoietic
stem and progenitor cell (HSPC) transplantation. Nfix-deficient HSPCs exhibit a severe loss …

MicroRNAs (miRNAs), a new class of noncoding RNAs, which can hybridize to target
messenger RNAs and regulate their expression posttranscriptionally, express differentially …