The field of microfluidics or lab-on-a-chip technology aims to improve and extend the
possibilities of bioassays, cell biology and biomedical research based on the idea of …

Microfluidic systems have shown unequivocal performance improvements over conventional
bench-top assays across a range of performance metrics. For example, specific advances …

To measure cell-to-cell variation in protein-mediated functions, we developed an approach
to conduct∼ 103 concurrent single-cell western blots (scWesterns) in∼ 4 h. A microscope …

In recent years, smart/stimuli-responsive hydrogels have drawn tremendous attention for
their varied applications, mainly in the biomedical field. These hydrogels are derived from …

Microfluidics is an emerging and promising interdisciplinary technology which offers
powerful platforms for precise production of novel functional materials (eg, emulsion …

Zymography is a technique for studying hydrolytic enzymes on the basis of substrate
degradation. It is a powerful, but often misinterpreted, tool yielding information on potential …

Rapid, quantitative Western blotting is a long-sought bioanalytical goal in the life sciences.
To this end, we describe a Western blotting assay conducted in a single glass microchannel …

Within just a few years, soil zymography has become accepted as an attractive and unique
approach for 2D map** of enzyme activities in intact soil samples. With zymography …

A dearth of protein isoform-based clinical diagnostics currently hinders advances in
personalized medicine. A well-organized protein biomarker validation process that includes …

We introduce an integrated microfluidic device consisting of a biomolecule concentrator and
a microdroplet generator, which enhances the limited sensitivity of low-abundance enzyme …