Long-term outcomes of deep brain stimulation in Parkinson disease

P Limousin, T Foltynie - Nature Reviews Neurology, 2019 - nature.com
The efficacy of deep brain stimulation (DBS) for Parkinson disease (PD) is well established
for up to 1 or 2 years, but long-term outcome data are still limited. In this Review, we critically …

Gastrointestinal dysfunction in Parkinson's disease

A Fasano, NP Visanji, LWC Liu, AE Lang… - The Lancet …, 2015 - thelancet.com
Our understanding of dysfunction of the gastrointestinal system in patients with Parkinson's
disease has increased substantially in the past decade. The entire gastrointestinal tract is …

Continuous intrajejunal infusion of levodopa-carbidopa intestinal gel for patients with advanced Parkinson's disease: a randomised, controlled, double-blind, double …

CW Olanow, K Kieburtz, P Odin, AJ Espay… - The Lancet …, 2014 - thelancet.com
Background Levodopa is the most effective therapy for Parkinson's disease, but chronic
treatment is associated with the development of potentially disabling motor complications …

Develo** consensus among movement disorder specialists on clinical indicators for identification and management of advanced Parkinson's disease: a multi …

A Antonini, AJ Stoessl, LS Kleinman… - … medical research and …, 2018 - Taylor & Francis
Background: Lack of a global consensus on the definition of advanced Parkinson's disease
(APD) and considerations for timing of device-aided therapies may result in heterogeneity in …

Recent strategies and advances in the fabrication of nano lipid carriers and their application towards brain targeting

M Agrawal, S Saraf, S Saraf, SK Dubey, A Puri… - Journal of Controlled …, 2020 - Elsevier
In last two decades, the lipid nanocarriers have been extensively investigated for their drug
targeting efficiency towards the critical areas of the human body like CNS, cardiac region …

Medical and surgical management of advanced Parkinson's disease

A Antonini, E Moro, C Godeiro… - Movement …, 2018 - Wiley Online Library
Advanced Parkinson's disease is characterized by the presence of motor fluctuations,
various degree of dyskinesia, and disability with functional impact on activities of daily living …

[HTML][HTML] Collective physician perspectives on non-oral medication approaches for the management of clinically relevant unresolved issues in Parkinson's disease …

P Odin, KR Chaudhuri, JT Slevin, J Volkmann… - Parkinsonism & Related …, 2015 - Elsevier
Navigate PD was an educational program established to supplement existing guidelines
and provide recommendations on the management of Parkinson's disease (PD) refractory to …

Expert consensus group report on the use of apomorphine in the treatment of Parkinson's disease–clinical practice recommendations

C Trenkwalder, KR Chaudhuri, PJG Ruiz… - Parkinsonism & related …, 2015 - Elsevier
Extensive published evidence supports the use of subcutaneously-administered
apomorphine as an effective therapy for Parkinson's disease (PD) but to date no consensus …

Levodopa-induced-dyskinesias clinical features, incidence, risk factors, management and impact on quality of life

A Manson, P Stirpe, A Schrag - Journal of Parkinson's disease, 2012 - content.iospress.com
Levodopa-induced dyskinesias (LID) belong to the most common dose-limiting adverse
effects of levodopa therapy.“Peak-dose” LID occur with the maximum effect of …

A sco** review of neurodegenerative manifestations in explainable digital phenoty**

H Alfalahi, SB Dias, AH Khandoker… - npj Parkinson's …, 2023 - nature.com
Neurologists nowadays no longer view neurodegenerative diseases, like Parkinson's and
Alzheimer's disease, as single entities, but rather as a spectrum of multifaceted symptoms …