NF-κB in biology and targeted therapy: new insights and translational implications

Q Guo, Y **, X Chen, X Ye, X Shen, M Lin… - Signal transduction and …, 2024 - nature.com
NF-κB signaling has been discovered for nearly 40 years. Initially, NF-κB signaling was
identified as a pivotal pathway in mediating inflammatory responses. However, with …

Physiological roles of hydrogen sulfide in mammalian cells, tissues, and organs

G Cirino, C Szabo… - Physiological …, 2023 - journals.physiology.org
Over the last two decades, hydrogen sulfide (H2S) has emerged as an endogenous
regulator of a broad range of physiological functions. H2S belongs to the class of molecules …

Exosomal microRNA‐155‐5p from PDLSCs regulated Th17/Treg balance by targeting sirtuin‐1 in chronic periodontitis

Y Zheng, C Dong, J Yang, Y **… - Journal of Cellular …, 2019 - Wiley Online Library
The mechanism of local inflammation and systemic injury in chronic periodontitis is
complicated, in which and exosomes play an important role. In our study, we found that T …

Hydrogen sulfide: an emerging precision strategy for gas therapy

H Ding, J Chang, F He, S Gai… - Advanced Healthcare …, 2022 - Wiley Online Library
Advances in nanotechnology have enabled the rapid development of stimuli‐responsive
therapeutic nanomaterials for precision gas therapy. Hydrogen sulfide (H2S) is a significant …

[HTML][HTML] Cashew (Anacardium occidentale L.) Nuts Counteract Oxidative Stress and Inflammation in an Acute Experimental Model of Carrageenan-Induced Paw …

M Cordaro, R Siracusa, R Fusco, R D'Amico… - Antioxidants, 2020 - mdpi.com
Background: Anacardium occidentale L. is a medicinal plant with powerful anti-oxidative and
anti-inflammatory properties. Acute inflammatory events cause tissue alterations, decrease …

Osteoclasts and osteoarthritis: novel intervention targets and therapeutic potentials during aging

H Wang, T Yuan, Y Wang, C Liu, D Li, Z Li, S Sun - Aging Cell, 2024 - Wiley Online Library
Osteoarthritis (OA), a chronic degenerative joint disease, is highly prevalent among the
aging population, and often leads to joint pain, disability, and a diminished quality of life …

Thioamides in medicinal chemistry and as small molecule therapeutic agents

G Huang, T Cierpicki, J Grembecka - European Journal of Medicinal …, 2024 - Elsevier
Thioamides, which are fascinating isosteres of amides, have garnered significant attention in
drug discovery and medicinal chemistry programs, spanning peptides and small molecule …

[HTML][HTML] Biochemical evaluation of the antioxidant effects of hydroxytyrosol on pancreatitis-associated gut injury

R Fusco, M Cordaro, R Siracusa, R D'Amico… - Antioxidants, 2020 - mdpi.com
Acute pancreatitis is a severe abdominal pathology often associated with several
complications including gut dysfunction. Oxidative stress is one of the most important …

Advances in In2O3-based materials for the development of hydrogen sulfide sensors

V Kumar, SM Majhi, KH Kim, HW Kim… - Chemical Engineering …, 2021 - Elsevier
The presence of H 2 S is an incisive indicator to assess the quality of indoor and/or outdoor
air. A number of metal oxide sensors have been developed to measure the concentration …

[HTML][HTML] Consumption of Anacardium occidentale L. (Cashew Nuts) Inhibits Oxidative Stress through Modulation of the Nrf2/HO−1 and NF-kB Pathways

R Fusco, M Cordaro, R Siracusa, AF Peritore… - Molecules, 2020 - mdpi.com
Ischemia/reperfusion injury is a severe disorder associated with a high mortality. Several
antioxidant and pharmacological properties of cashew nuts (Anacardium occidentale L.) and …