Strategies to convert organic fluorophores into red/near-infrared emitting analogues and their utilization in bioimaging probes
Organic fluorophores aided by current microscopy imaging modalities are essential for
studying biological systems. Recently, red/near-infrared emitting fluorophores have attracted …
studying biological systems. Recently, red/near-infrared emitting fluorophores have attracted …
Activatable Probes for Ratiometric Imaging of Endogenous Biomarkers In Vivo
Q Fu, X Yang, M Wang, K Zhu, Y Wang, J Song - ACS nano, 2024 - ACS Publications
Dynamic variations in the concentration and abnormal distribution of endogenous
biomarkers are strongly associated with multiple physiological and pathological states …
biomarkers are strongly associated with multiple physiological and pathological states …
Conformation of the Ester Group Governs the Photophysics of Highly Polarized Benzo[g]coumarins
Photosensitizers that display “unusual” emission from upper electronically excited states
offer possibilities for initiating higher-energy processes than what the governing Kasha's rule …
offer possibilities for initiating higher-energy processes than what the governing Kasha's rule …
Interactive Twin Intramolecular Hydrogen Bonds Enable Bright, S‐Blue Emissive, Environment‐Insensitive Single‐Benzene Fluorophores
Small‐molecule dyes that emit blue fluorescence, particularly those that emit in the S‐blue
region, are limited in number. Functionalization of benzene with electron‐donating and …
region, are limited in number. Functionalization of benzene with electron‐donating and …
Rapid point-of-care quantification of human serum albumin in urine based on ratiometric fluorescence signaling driven by intramolecular H-bonding
Human serum albumin exerts multifunctions, such as maintaining the oncotic pressure of
plasma, carrying hydrophobic molecules, and acting as the most important antioxidant in the …
plasma, carrying hydrophobic molecules, and acting as the most important antioxidant in the …
Cell-Membrane-Localizing Fluorescence Probes for Aminopeptidase N
Aminopeptidase N (APN), a transmembrane ectoenzyme, plays multifunctional roles in cell
survival and migration, angiogenesis, blood pressure regulation, and viral uptake …
survival and migration, angiogenesis, blood pressure regulation, and viral uptake …
Rationally designed two-photon ratiometric elastase probe for investigating inflammatory bowel disease
Elastase, a serine protease, plays important roles in our body in food digestion and defence
against pathogens. Particularly, the elastase present in neutrophils is directly associated …
against pathogens. Particularly, the elastase present in neutrophils is directly associated …
A General Strategy Toward pH‐Resistant Phenolic Fluorophores for High‐Fidelity Sensing and Bioimaging Applications
Aryl alcohol‐type or phenolic fluorophores offer diverse opportunities for develo**
bioimaging agents and fluorescence probes. Due to the inherently acidic hydroxyl …
bioimaging agents and fluorescence probes. Due to the inherently acidic hydroxyl …
Fluorescence imaging of mitochondrial DNA base excision repair reveals dynamics of oxidative stress responses
Mitochondrial function in cells declines with aging and with neurodegeneration, due in large
part to accumulated mutations in mitochondrial DNA (mtDNA) that arise from deficient DNA …
part to accumulated mutations in mitochondrial DNA (mtDNA) that arise from deficient DNA …
Nad (p) h quinone oxidoreductase-1 in organ and tumor tissues: Distinct activity levels observed with a benzo-rosol-based dual-excitation and dual-emission probe
NAD (P) H quinone oxidoreductase-1 (NQO1), a protective enzyme against cellular
oxidative stress, is expressed abnormally high in solid tumors and thus recognized as a …
oxidative stress, is expressed abnormally high in solid tumors and thus recognized as a …