[HTML][HTML] The role of iron in the pathogenesis of COVID-19 and possible treatment with lactoferrin and other iron chelators

HM Habib, S Ibrahim, A Zaim, WH Ibrahim - Biomedicine & …, 2021 - Elsevier
Iron overload is increasingly implicated as a contributor to the pathogenesis of COVID-19.
Indeed, several of the manifestations of COVID-19, such as inflammation, hypercoagulation …

Diverse mechanisms of antimicrobial activities of lactoferrins, lactoferricins, and other lactoferrin-derived peptides

Š Gruden, N Poklar Ulrih - International journal of molecular sciences, 2021 - mdpi.com
Lactoferrins are an iron-binding glycoprotein that have important protective roles in the
mammalian body through their numerous functions, which include antimicrobial, antitumor …

The biology of lactoferrin, an iron-binding protein that can help defend against viruses and bacteria

DB Kell, EL Heyden, E Pretorius - Frontiers in immunology, 2020 - frontiersin.org
Lactoferrin is a nutrient classically found in mammalian milk. It binds iron and is transferred
via a variety of receptors into and between cells, serum, bile, and cerebrospinal fluid. It has …

Antimicrobial properties of colostrum and milk

F Eker, E Akdaşçi, H Duman, YM Yalçıntaş… - Antibiotics, 2024 - mdpi.com
The growing number of antibiotic resistance genes is putting a strain on the ecosystem and
harming human health. In addition, consumers have developed a cautious attitude towards …

Nutraceutical and health-promoting potential of lactoferrin, an iron-binding protein in human and animal: current knowledge

MF Ashraf, D Zubair, MN Bashir, M Alagawany… - … Trace Element Research, 2024 - Springer
Lactoferrin is a natural cationic iron-binding glycoprotein of the transferrin family found in
bovine milk and other exocrine secretions, including lacrimal fluid, saliva, and bile …

Lactoferrin: major physiological functions and applications

L Hao, Q Shan, J Wei, F Ma… - Current Protein and …, 2019 - benthamdirect.com
Lactoferrin (lactotransferrin; Lf) is an iron-binding glycoprotein and one of the most important
bioactivators in milk and other external secretions. It has numerous biological roles …

A review of the biological activities of lactoferrin: Mechanisms and potential applications

R Hong, A **e, C Jiang, Y Guo, Y Zhang, J Chen… - Food & Function, 2024 - pubs.rsc.org
Lactoferrin, a multifunctional iron-binding protein found in milk and other body fluids,
possesses numerous biological activities. The functional activity of lactoferrin lies not only in …

Lactoferrin: A glycoprotein involved in immunomodulation, anticancer, and antimicrobial processes

Q Rascón-Cruz, EA Espinoza-Sánchez… - Molecules, 2021 - mdpi.com
Lactoferrin is an iron binding glycoprotein with multiple roles in the body. Its participation in
apoptotic processes in cancer cells, its ability to modulate various reactions of the immune …

[HTML][HTML] Milk proteins—Their biological activities and use in cosmetics and dermatology

K Kazimierska, U Kalinowska-Lis - Molecules, 2021 - mdpi.com
Milk and colostrum have high biological potential, and due to their natural origin and non-
toxicity, they have many uses in cosmetics and dermatology. Research is ongoing on their …

[HTML][HTML] Lactoferrin and its derived peptides: an alternative for combating virulence mechanisms developed by pathogens

D Zarzosa-Moreno, C Avalos-Gómez… - Molecules, 2020 - mdpi.com
Due to the emergence of multidrug-resistant pathogens, it is necessary to develop options to
fight infections caused by these agents. Lactoferrin (Lf) is a cationic nonheme multifunctional …