A Photoactivated Self‐Assembled Nanoreactor for Inducing Cascade‐Amplified Oxidative Stress toward Type I Photodynamic Therapy in Hypoxic Tumors

X Luo, Q Jiao, S Pei, S Zhou, Y Zheng… - Advanced …, 2024 - Wiley Online Library
Type I photodynamic therapy (PDT) generates reactive oxygen species (ROS) through
oxygen‐independent photoreactions, making it a promising method for treating hypoxic …

Isothermal nucleic acid amplification for monitoring hand-foot-and-mouth disease: current status and future implications

Z Chen, K Mao, Z Chen, R Feng, W Du, H Zhang… - Microchimica Acta, 2025 - Springer
With the global prevalence of the hand-foot-and-mouth disease (HFMD) epidemic, the
development of reliable point-of-care testing (POCT) is crucial for the timely identification …

Sensitivity-Enhanced Hydrogel Digital RT-LAMP with In Situ Enrichment and Interfacial Reaction for Norovirus Quantification in Food and Water

T Yang, L Xue, Z Luo, J Lin, X Zhang, F **ao… - Journal of Hazardous …, 2025 - Elsevier
Low levels of human norovirus (HuNoV) in food and environment present challenges for
nucleic acid detection. This study reported an evaporation-enhanced hydrogel digital …

Construction of a microfluidic SELEX platform for efficient screening of advanced glycation end products aptamer

S Zhang, Z Ning, Y Zhang, X Lin, N Duan… - Biosensors and …, 2025 - Elsevier
Aptamers, as a kind of recognition molecules with stable nature and excellent binding ability,
are usually obtained by systematic evolution of ligands by exponential enrichment (SELEX) …

A Portable Nucleic Acid Testing Platform with Photosensitization, a Three-Dimensionally Printed Multipiece Chip, and Digital Color Sensing

T Dong, R Ding, R Zhou, C Shen, W Sheridan… - Analytical …, 2024 - ACS Publications
Portable nucleic acid testing (NAT) holds great promise for point-of-care disease diagnosis
and field-based applications but remains difficult to achieve. Herein, we describe a portable …

Advancing Rapid Detection of Respiratory Pathogens Using Microfluidic Chip

JX Lai, YR Qin, YW Liao, YT Si, Q Yuan… - JoVE (Journal of …, 2024 - jove.com
Respiratory tract infections (RTIs) are among the most common problems in clinical settings.
Rapid and accurate identification of bacterial pathogens will provide practical guidelines for …