SNT: a unifying toolbox for quantification of neuronal anatomy

C Arshadi, U Günther, M Eddison, KIS Harrington… - Nature …, 2021 - nature.com
SNT is an end-to-end framework for neuronal morphometry and whole-brain connectomics
that supports tracing, proof-editing, visualization, quantification and modeling of …

How neurons exploit fractal geometry to optimize their network connectivity

JH Smith, C Rowland, B Harland, S Moslehi… - Scientific reports, 2021 - nature.com
We investigate the degree to which neurons are fractal, the origin of this fractality, and its
impact on functionality. By analyzing three-dimensional images of rat neurons, we show the …

An innate immune response to adeno-associated virus genomes decreases cortical dendritic complexity and disrupts synaptic transmission

CM Suriano, N Kumar, JL Verpeut, J Ma, C Jung… - Molecular Therapy, 2024 - cell.com
Recombinant adeno-associated viruses (AAVs) allow rapid and efficient gene delivery to the
nervous system, are widely used in neuroscience research, and are the basis of FDA …

Direct induction of microtubule branching by microtubule nucleation factor SSNA1

N Basnet, H Nedozralova, AH Crevenna… - Nature cell …, 2018 - nature.com
Microtubules are central elements of the eukaryotic cytoskeleton that often function as part of
branched networks. Current models for branching include nucleation of new microtubules …

Topography of a visuomotor transformation

TO Helmbrecht, M Dal Maschio, JC Donovan… - Neuron, 2018 - cell.com
The brain converts perceptual information into appropriate patterns of muscle activity
depending on the categorization and localization of sensory cues. Sensorimotor information …

A modular framework for multi-scale tissue imaging and neuronal segmentation

S Cauzzo, E Bruno, D Boulet, P Nazac, M Basile… - Nature …, 2024 - nature.com
The development of robust tools for segmenting cellular and sub-cellular neuronal structures
lags behind the massive production of high-resolution 3D images of neurons in brain tissue …

Using simulated training data of voxel-level generative models to improve 3D neuron reconstruction

C Liu, D Wang, H Zhang, W Wu, W Sun… - IEEE transactions on …, 2022 - ieeexplore.ieee.org
Reconstructing neuron morphologies from fluorescence microscope images plays a critical
role in neuroscience studies. It relies on image segmentation to produce initial masks either …

[HTML][HTML] Topology recapitulates morphogenesis of neuronal dendrites

M Liao, AD Bird, H Cuntz, J Howard - Cell reports, 2023 - cell.com
Branching allows neurons to make synaptic contacts with large numbers of other neurons,
facilitating the high connectivity of nervous systems. Neuronal arbors have geometric …

Stages and transitions in dendrite arbor differentiation

LF Yoong, YJ Pai, AW Moore - Neuroscience Research, 2019 - Elsevier
Neurons connect through dendrite arbors to receive inputs from their appropriate partners.
The branching pattern, size, and input distribution in the arbor determine neuron function …

How axon and dendrite branching are guided by time, energy, and spatial constraints

P Desai-Chowdhry, AB Brummer, VM Savage - Scientific Reports, 2022 - nature.com
Neurons are connected by complex branching processes—axons and dendrites—that
process information for organisms to respond to their environment. Classifying neurons …