The development of liver fibrosis primarily determines quality of life as well as prognosis.
Animal models are often used to model and understand the underlying mechanisms of …

TREM1 and TREM2 are members of the triggering receptors expressed on myeloid cells
(TREM) family. Both TREM1 and TREM2 are immunoglobulin superfamily receptors. Their …

Background Ganoderma lucidum polysaccharide (GLP) has many biological properties,
however, the anti-fibrosis effect of GLP is unknown at present. Purpose This study aimed to …

Non-alcoholic fatty liver disease (NAFLD) and non-alcoholic steatohepatitis (NASH) are a
growing epidemic and the most common liver diseases. Consumption of a western diet with …

Background Liver fibrosis (LF) is a trauma repair process carried out by the liver in response
to various acute and chronic liver injuries. Its primary pathological characteristics are …

Acute pancreatitis (AP) is a potential gastrointestinal problem most commonly associated
with pancreatic inflammation and acinar cells injury. Nimbolide (NB), isolated from the tree …

Borneol is a commonly used flavouring substance in traditional Chinese medicine, which
possesses several pharmacological activities including analgesic, antiinflammatory, and …

Piperlongumine (PL) is an alkaloid from Piper longum L. with anti-inflammatory and
antitumor properties. Numerous studies have focused on its antitumor effect. However, the …

Piperlongumine (PL) and piperine (PP) are alkaloids presented in long pepper (Piper
longum), and they exhibit various biological activities, especially anti-cancer properties. With …

Bile duct injury (BDI) and bile tract diseases are regarded as prominent challenges in
hepatobiliary surgery due to the risk of severe complications. Hepatobiliary, pancreatic, and …