Since the discovery of X-ray diffraction and its potential to elucidate crystal symmetry,
powder X-ray diffraction has found diverse applications in the field of pharmaceutical …

For poorly water soluble drugs, the amorphous state provides an avenue to enhance oral
bioavailability. The preparation method, in addition to sample history, can dictate the nature …

An indispensable resource for researchers and students in materials science, chemistry,
physics, and pharmaceuticals Written by one of the pioneers of 2D X-Ray Diffraction, this …

A new Raman subtechnique, spatially offset low-frequency Raman spectroscopy (SOLFRS),
is demonstrated via an analysis of pharmaceutical solid dosage forms. Several different …

Prevalent polymorphism and complicated phase behavior of active pharmaceutical
ingredients (APIs) often result in remarkable differences in the respective biochemical and …

Tablets which were binary mixtures of pioglitazone hydrochloride (PioHCl) with magnesium
stearate (MgSt), croscarmellose sodium (CCS), microcrystalline cellulose, or lactose …

Fluid bed coating has been shown to be a suitable manufacturing technique to formulate
poorly soluble drugs in glass solutions. Layering inert carriers with a drug–polymer mixture …

Surface-driven isothermal dehydration of model tablets containing citric acid monohydrate
was investigated using spatially offset low-frequency Raman spectroscopy (SOLFRS) …

One unusual and challenging scientific field that has received only cursory attention to date
is the three-dimensional (3D) microstructure and spatial distribution of drug (s) and …

Our objective was to monitor the surface crystallization in disordered caffeine-oxalic acid
(CAFOXA) cocrystals following exposure to elevated water vapor pressure. This was …