Harnessing nanomaterials for cancer sonodynamic immunotherapy
Immunotherapy has made remarkable strides in cancer therapy over the past decade.
However, such emerging therapy still suffers from the low response rates and immune …
However, such emerging therapy still suffers from the low response rates and immune …
Self-assembled mRNA vaccines
Abstract mRNA vaccines have evolved from being a mere curiosity to emerging as COVID-
19 vaccine front-runners. Recent advancements in the field of RNA technology, vaccinology …
19 vaccine front-runners. Recent advancements in the field of RNA technology, vaccinology …
Vaccine-like nanomedicine for cancer immunotherapy
Y Yi, M Yu, W Li, D Zhu, L Mei, M Ou - Journal of Controlled Release, 2023 - Elsevier
The successful clinical application of immune checkpoint blockade (ICB) and chimeric
antigen receptor T cells (CAR-T) therapeutics has attracted extensive attention to …
antigen receptor T cells (CAR-T) therapeutics has attracted extensive attention to …
Microfluidic formulation of nanoparticles for biomedical applications
Nanomedicine has made significant advances in clinical applications since the late-20th
century, in part due to its distinct advantages in biocompatibility, potency, and novel …
century, in part due to its distinct advantages in biocompatibility, potency, and novel …
Concepts of nanoparticle cellular uptake, intracellular trafficking, and kinetics in nanomedicine
Nanoparticle-based therapeutics and diagnostics are commonly referred to as
nanomedicine and may significantly impact the future of healthcare. However, the clinical …
nanomedicine and may significantly impact the future of healthcare. However, the clinical …
Advances in mRNA vaccines for infectious diseases
During the last two decades, there has been broad interest in RNA-based technologies for
the development of prophylactic and therapeutic vaccines. Preclinical and clinical trials have …
the development of prophylactic and therapeutic vaccines. Preclinical and clinical trials have …
Ionizable lipid nanoparticle-mediated mRNA delivery for human CAR T cell engineering
Chimeric antigen receptor (CAR) T cell therapy relies on the ex vivo manipulation of patient
T cells to create potent, cancer-targeting therapies, shown to be capable of inducing …
T cells to create potent, cancer-targeting therapies, shown to be capable of inducing …
Bioinspired and biomimetic delivery platforms for cancer vaccines
Cancer vaccines aim at eliciting tumor‐specific responses for the immune system to identify
and eradicate malignant tumor cells while sparing the normal tissues. Furthermore, cancer …
and eradicate malignant tumor cells while sparing the normal tissues. Furthermore, cancer …
PLGA-based nanomedicine: history of advancement and development in clinical applications of multiple diseases
Research on the use of biodegradable polymers for drug delivery has been ongoing since
they were first used as bioresorbable surgical devices in the 1980s. For tissue engineering …
they were first used as bioresorbable surgical devices in the 1980s. For tissue engineering …
Microneedles for painless transdermal immunotherapeutic applications
Immunotherapy has recently garnered plenty of attention to improve the clinical outcomes in
the treatment of various diseases. However, owing to the dynamic nature of the immune …
the treatment of various diseases. However, owing to the dynamic nature of the immune …