Advances in nanomaterial-based targeted drug delivery systems

X Cheng, Q **e, Y Sun - Frontiers in bioengineering and …, 2023 - frontiersin.org
Nanomaterial-based drug delivery systems (NBDDS) are widely used to improve the safety
and therapeutic efficacy of encapsulated drugs due to their unique physicochemical and …

Where is nano today and where is it headed? A review of nanomedicine and the dilemma of nanotoxicology

C Domingues, A Santos, C Alvarez-Lorenzo… - ACS …, 2022 - ACS Publications
Worldwide nanotechnology development and application have fueled many scientific
advances, but technophilic expectations and technophobic demands must be …

The emerging role of nanotechnology in plant genetic engineering

HJ Squire, S Tomatz, E Voke… - Nature Reviews …, 2023 - nature.com
Genetic engineering to improve the capabilities of plants is essential given climate change
and population growth pressures. Current manipulation methods are laborious and species …

Nanotechnology-enhanced immunotherapy for metastatic cancer

P Zhang, J Meng, Y Li, C Yang, Y Hou, W Tang… - The Innovation, 2021 - cell.com
A vast majority of cancer deaths occur as a result of metastasis. Unfortunately, effective
treatments for metastases are currently lacking due to the difficulty of selectively targeting …

Overcoming tumor microenvironment obstacles: current approaches for boosting nanodrug delivery

X Wang, H Zhang, X Chen, C Wu, K Ding, G Sun… - Acta Biomaterialia, 2023 - Elsevier
In order to achieve targeted delivery of anticancer drugs, efficacy improvement, and side
effect reduction, various types of nanoparticles are employed. However, their therapeutic …

Exosome-transported circRNA_0001236 enhances chondrogenesis and suppress cartilage degradation via the miR-3677-3p/Sox9 axis

G Mao, Y Xu, D Long, H Sun, H Li, R **n… - Stem Cell Research & …, 2021 - Springer
Objectives Aberrations in exosomal circular RNA (circRNA) expression have been identified
in various human diseases. In this study, we investigated whether exosomal circRNAs could …

Recent advances of nanomaterials for intervention in Parkinson's disease in the context of anti-inflammation

R Zhang, X Chen, Y Cheng, Z Chen, X Li… - Coordination Chemistry …, 2024 - Elsevier
Inflammation and neuroinflammation play critical roles in the pathogenesis of
neurodegenerative diseases such as Parkinson's disease (PD). Nanomaterials with reactive …

Microfluidic synthesis of nanomaterials for biomedical applications

Y Huang, C Liu, Q Feng, J Sun - Nanoscale Horizons, 2023 - pubs.rsc.org
The field of nanomaterials has progressed dramatically over the past decades with important
contributions to the biomedical area. The physicochemical properties of nanomaterials, such …

Biomimetic immunomodulation strategies for effective tissue repair and restoration

RA Villarreal-Leal, GD Healey, B Corradetti - Advanced drug delivery …, 2021 - Elsevier
Inflammation plays a central role in wound healing following injury or disease and is
mediated by a precise cascade of cellular and molecular events. Unresolved inflammatory …

Biomimetic surface-enhanced Raman scattering nanoparticles with improved dispersibility, signal brightness, and tumor targeting functions

I Srivastava, R Xue, J Jones, H Rhee, K Flatt, V Gruev… - ACS …, 2022 - ACS Publications
The development of biocompatible and nontoxic surface-enhanced Raman scattering
(SERS) nanoparticles is of considerable current interest because of their attractive …