Bacterial siderophores in community and host interactions

J Kramer, Ö Özkaya, R Kümmerli - Nature Reviews Microbiology, 2020 - nature.com
Iron is an essential trace element for most organisms. A common way for bacteria to acquire
this nutrient is through the secretion of siderophores, which are secondary metabolites that …

Spatial structure, cooperation and competition in biofilms

CD Nadell, K Drescher, KR Foster - Nature Reviews Microbiology, 2016 - nature.com
Bacteria often live within matrix-embedded communities, termed biofilms, which are now
understood to be a major mode of microbial life. The study of biofilms has revealed their vast …

[PDF][PDF] Classifying the evolutionary and ecological features of neoplasms

CC Maley, A Aktipis, TA Graham, A Sottoriva… - Nature Reviews …, 2017 - nature.com
Neoplasms change over time through a process of cell-level evolution, driven by genetic
and epigenetic alterations. However, the ecology of the microenvironment of a neoplastic …

The mechanical world of bacteria

A Persat, CD Nadell, MK Kim, F Ingremeau… - Cell, 2015 - cell.com
In the wild, bacteria are predominantly associated with surfaces as opposed to existing as
free-swimming, isolated organisms. They are thus subject to surface-specific mechanics …

Solutions to the public goods dilemma in bacterial biofilms

K Drescher, CD Nadell, HA Stone, NS Wingreen… - Current Biology, 2014 - cell.com
Bacteria frequently live in densely populated surface-bound communities, termed biofilms [1–
4]. Biofilm-dwelling cells rely on secretion of extracellular substances to construct their …

Killing by Type VI secretion drives genetic phase separation and correlates with increased cooperation

L McNally, E Bernardy, J Thomas, A Kalziqi… - Nature …, 2017 - nature.com
By nature of their small size, dense growth and frequent need for extracellular metabolism,
microbes face persistent public goods dilemmas. Genetic assortment is the only general …

Iron acquisition strategies in pseudomonads: mechanisms, ecology, and evolution

R Kümmerli - Biometals, 2023 - Springer
Iron is important for bacterial growth and survival, as it is a common co-factor in essential
enzymes. Although iron is very abundant in the earth crust, its bioavailability is low in most …

Investigating the dynamics of microbial consortia in spatially structured environments

S Gupta, TD Ross, MM Gomez, JL Grant… - Nature …, 2020 - nature.com
The spatial organization of microbial communities arises from a complex interplay of biotic
and abiotic interactions, and is a major determinant of ecosystem functions. Here we design …

Environmentally mediated social dilemmas

S Estrela, E Libby, J Van Cleve, F Débarre… - Trends in ecology & …, 2019 - cell.com
By consuming and producing environmental resources, organisms inevitably change their
habitats. The consequences of such environmental modifications can be detrimental or …

Spatial dilemmas of diffusible public goods

B Allen, J Gore, MA Nowak - Elife, 2013 - elifesciences.org
The emergence of cooperation is a central question in evolutionary biology. Microorganisms
often cooperate by producing a chemical resource (a public good) that benefits other cells …