Abstract Skeletal muscle makes up 30–40% of the total body mass. It is of great significance
in maintaining digestion, inhaling and exhaling, sustaining body posture, exercising …

Ubiquitination is an important post-translational modification (PTM) for protein substrates,
whereby ubiquitin is added to proteins through the coordinated activity of activating (E1) …

Ubiquitin conjugating enzyme E2 is an important component of the post-translational protein
ubiquitination pathway, which mediates the transfer of activated ubiquitin to substrate …

In the autumn of 2021, the 2022 Padua Days of Muscle and Mobility Medicine (PDM3) was
planned to be held from March 30 to April 2, 2022. Despite the fact that Coronavirus COVID …

The field of the Tripartite Motif (TRIM) family has progressively attracted increasing interest
during the last two decades. The presence of a distinctive amino-terminal module …

Skeletal muscle tissue increases or decreases its volume by synthesizing or degrading
myofibrillar proteins. The ubiquitin–proteasome system plays a pivotal role during muscle …

Lung cancer is the leading cause of cancer-related mortality, and the deaths are mostly
attributed to distant metastasis. Previous studies have demonstrated that ubiquitin …

Spinal muscular atrophy (SMA) is one of the most frequent causes of death in childhood.
The disease's molecular basis is deletion or mutations in the SMN1 gene, which produces …

Muscle mass development depends on increased protein synthesis and reduced muscle
protein degradation. Muscle ring-finger protein-1 (MuRF1) plays a key role in controlling …

Background/Objectives: Muscle-specific RING finger protein 1 (MuRF-1) is a pivotal
regulator of muscle protein breakdown, an essential process for post-exercise muscle …