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Spectral pre-processing for biomedical vibrational spectroscopy and microspectroscopic imaging
Recent years have seen substantial progress toward the application of infrared (IR) and
Raman spectroscopy as useful analytical tools in biomedical research. Vibrational …
Raman spectroscopy as useful analytical tools in biomedical research. Vibrational …
Emerging themes in image informatics and molecular analysis for digital pathology
Pathology is essential for research in disease and development, as well as for clinical
decision making. For more than 100 years, pathology practice has involved analyzing …
decision making. For more than 100 years, pathology practice has involved analyzing …
Using Fourier transform IR spectroscopy to analyze biological materials
IR spectroscopy is an excellent method for biological analyses. It enables the
nonperturbative, label-free extraction of biochemical information and images toward …
nonperturbative, label-free extraction of biochemical information and images toward …
Fast infrared chemical imaging with a quantum cascade laser
Infrared (IR) spectroscopic imaging systems are a powerful tool for visualizing molecular
microstructure of a sample without the need for dyes or stains. Table-top Fourier transform …
microstructure of a sample without the need for dyes or stains. Table-top Fourier transform …
Infrared spectroscopic imaging advances as an analytical technology for biomedical sciences
Optical chemical imaging seeks to nondestructively acquire spatially resolved chemical
information without the use of labels or probes. The combination of vibrational mid-infrared …
information without the use of labels or probes. The combination of vibrational mid-infrared …
Label-free live-cell imaging with confocal Raman microscopy
Confocal Raman spectroscopy is a noninvasive alternative to established cell imaging
methods because it does not require chemical fixation, the use of fluorescent markers, or …
methods because it does not require chemical fixation, the use of fluorescent markers, or …
Raman spectroscopy-based sensitive and specific detection of glycated hemoglobin
In recent years, glycated hemoglobin (HbA1c) has been increasingly accepted as a
functional metric of mean blood glucose in the treatment of diabetic patients. Importantly …
functional metric of mean blood glucose in the treatment of diabetic patients. Importantly …
Infrared spectral histopathology (SHP): a novel diagnostic tool for the accurate classification of lung cancer
We report results of a study utilizing a recently developed tissue diagnostic method, based
on label-free spectral techniques, for the classification of lung cancer histopathological …
on label-free spectral techniques, for the classification of lung cancer histopathological …
High-definition infrared spectroscopic imaging
The quality of images from an infrared (IR) microscope has traditionally been limited by
considerations of throughput and signal-to-noise ratio (SNR). An understanding of the …
considerations of throughput and signal-to-noise ratio (SNR). An understanding of the …
Rapid hyperspectral photothermal mid-infrared spectroscopic imaging from sparse data for gynecologic cancer tissue subty**
Ovarian cancer detection has traditionally relied on a multistep process that includes biopsy,
tissue staining, and morphological analysis by experienced pathologists. While widely …
tissue staining, and morphological analysis by experienced pathologists. While widely …