Applications of machine learning in human microbiome studies: a review on feature selection, biomarker identification, disease prediction and treatment
LJ Marcos-Zambrano… - Frontiers in …, 2021 - frontiersin.org
The number of microbiome-related studies has notably increased the availability of data on
human microbiome composition and function. These studies provide the essential material …
human microbiome composition and function. These studies provide the essential material …
Gut OncoMicrobiome Signatures (GOMS) as next-generation biomarkers for cancer immunotherapy
Oncogenesis is associated with intestinal dysbiosis, and stool shotgun metagenomic
sequencing in individuals with this condition might constitute a non-invasive approach for …
sequencing in individuals with this condition might constitute a non-invasive approach for …
The person-to-person transmission landscape of the gut and oral microbiomes
The human microbiome is an integral component of the human body and a co-determinant
of several health conditions,. However, the extent to which interpersonal relations shape the …
of several health conditions,. However, the extent to which interpersonal relations shape the …
Intestinal Akkermansia muciniphila predicts clinical response to PD-1 blockade in patients with advanced non-small-cell lung cancer
Aside from PD-L1 expression, biomarkers of response to immune checkpoint inhibitors (ICIs)
in non-small-cell lung cancer (NSCLC) are needed. In a previous retrospective analysis, we …
in non-small-cell lung cancer (NSCLC) are needed. In a previous retrospective analysis, we …
Identification of antimicrobial peptides from the human gut microbiome using deep learning
The human gut microbiome encodes a large variety of antimicrobial peptides (AMPs), but
the short lengths of AMPs pose a challenge for computational prediction. Here we combined …
the short lengths of AMPs pose a challenge for computational prediction. Here we combined …
Improved metagenome binning and assembly using deep variational autoencoders
Despite recent advances in metagenomic binning, reconstruction of microbial species from
metagenomics data remains challenging. Here we develop variational autoencoders for …
metagenomics data remains challenging. Here we develop variational autoencoders for …
Combinatorial, additive and dose-dependent drug–microbiome associations
During the transition from a healthy state to cardiometabolic disease, patients become
heavily medicated, which leads to an increasingly aberrant gut microbiome and serum …
heavily medicated, which leads to an increasingly aberrant gut microbiome and serum …
Resistant starch decreases intrahepatic triglycerides in patients with NAFLD via gut microbiome alterations
Y Ni, L Qian, SL Siliceo, X Long, E Nychas, Y Liu… - Cell Metabolism, 2023 - cell.com
Non-alcoholic fatty liver disease (NAFLD) is a hepatic manifestation of metabolic dysfunction
for which effective interventions are lacking. To investigate the effects of resistant starch (RS) …
for which effective interventions are lacking. To investigate the effects of resistant starch (RS) …
The gut microbiota in prediabetes and diabetes: a population-based cross-sectional study
The link between the gut microbiota and type 2 diabetes (T2D) warrants further investigation
because of known confounding effects from antidiabetic treatment. Here, we profiled the gut …
because of known confounding effects from antidiabetic treatment. Here, we profiled the gut …
Microbiome connections with host metabolism and habitual diet from 1,098 deeply phenotyped individuals
The gut microbiome is shaped by diet and influences host metabolism; however, these links
are complex and can be unique to each individual. We performed deep metagenomic …
are complex and can be unique to each individual. We performed deep metagenomic …