A complex systems approach to aging biology

AA Cohen, L Ferrucci, T Fülöp, D Gravel, N Hao… - Nature aging, 2022‏ - nature.com
Having made substantial progress understanding molecules, cells, genes and pathways,
aging biology research is now moving toward integration of these parts, attempting to …

[HTML][HTML] Applications of machine learning in real-life digital health interventions: review of the literature

AK Triantafyllidis, A Tsanas - Journal of medical Internet research, 2019‏ - jmir.org
Background Machine learning has attracted considerable research interest toward
develo** smart digital health interventions. These interventions have the potential to …

The new field of network physiology: building the human physiolome

PC Ivanov - Frontiers in network physiology, 2021‏ - frontiersin.org
The human organism comprises various physiological and organ systems, each with its own
structural organization and functional complexity, leading to complex, transient, fluctuating …

Network physiology: how organ systems dynamically interact

RP Bartsch, KKL Liu, A Bashan, PC Ivanov - PloS one, 2015‏ - journals.plos.org
We systematically study how diverse physiologic systems in the human organism
dynamically interact and collectively behave to produce distinct physiologic states and …

Detection of COVID-19 using multimodal data from a wearable device: results from the first TemPredict Study

AE Mason, FM Hecht, SK Davis, JL Natale… - Scientific reports, 2022‏ - nature.com
Early detection of diseases such as COVID-19 could be a critical tool in reducing disease
transmission by hel** individuals recognize when they should self-isolate, seek testing …

Is metabolic rate a universal 'pacemaker'for biological processes?

DS Glazier - Biological Reviews, 2015‏ - Wiley Online Library
ABSTRACT A common, long‐held belief is that metabolic rate drives the rates of various
biological, ecological and evolutionary processes. Although this metabolic pacemaker view …

A Comparative Study of ECG-derived Respiration in Ambulatory Monitoring using the Single-lead ECG

C Varon, J Morales, J Lázaro, M Orini, M Deviaene… - Scientific reports, 2020‏ - nature.com
Cardiorespiratory monitoring is crucial for the diagnosis and management of multiple
conditions such as stress and sleep disorders. Therefore, the development of ambulatory …

Dynamic coupling between the central and autonomic nervous systems during sleep: a review

M de Zambotti, J Trinder, A Silvani, IM Colrain… - Neuroscience & …, 2018‏ - Elsevier
Sleep is characterized by coordinated cortical and cardiac oscillations reflecting
communication between the central (CNS) and autonomic (ANS) nervous systems. Here, we …

Network physiology of exercise: vision and perspectives

N Balagué, R Hristovski, M Almarcha… - Frontiers in …, 2020‏ - frontiersin.org
The basic theoretical assumptions of Exercise Physiology and its research directions,
strongly influenced by reductionism, may hamper the full potential of basic science …

Seizure detection algorithm based on improved functional brain network structure feature extraction

L Jiang, J He, H Pan, D Wu, T Jiang, J Liu - Biomedical Signal Processing …, 2023‏ - Elsevier
Epilepsy is one of the most common neurological disorders. Accurate detection of epileptic
seizures is essential for treatment. A seizure detection method with the structure of functional …