Marine natural products
Covering: 2016. Previous review: Nat. Prod. Rep., 2017, 34, 235–294 This review covers the
literature published in 2016 for marine natural products (MNPs), with 757 citations (643 for …
literature published in 2016 for marine natural products (MNPs), with 757 citations (643 for …
Recent advances in Wacker oxidation: from conventional to modern variants and applications
This review emphasizes the recent developments in the Wacker oxidation process from its
conventional form to more efficient, economical, and greener methods established in the last …
conventional form to more efficient, economical, and greener methods established in the last …
Unconventional macrocyclizations in natural product synthesis
Over the past several decades, macrocyclic compounds have emerged as increasingly
significant therapeutic candidates in drug discovery. Their pharmacological activity hinges …
significant therapeutic candidates in drug discovery. Their pharmacological activity hinges …
Intramolecular heck reaction in total synthesis of natural products: an update
This review highlights the application of intramolecular Heck reaction in total synthesis of
natural products which were successfully synthesized in recent years (2013 to 2019). Heck …
natural products which were successfully synthesized in recent years (2013 to 2019). Heck …
Heck macrocyclization in natural product total synthesis
W Zhang - Natural Product Reports, 2021 - pubs.rsc.org
Covering: 1981–2020 Heck macrocyclization is a logical extension of the award-winning
Mizoroki–Heck reaction. Through covalent linking of two otherwise discrete coupling …
Mizoroki–Heck reaction. Through covalent linking of two otherwise discrete coupling …
Electronic asymmetry of an annelated pyridyl–mesoionic carbene scaffold: application in Pd (II)-Catalyzed wacker-type oxidation of olefins
The two donor modules of an annelated pyridyl–mesoionic carbene ligand (aPmic) have
different σ-and π-bonding characteristics leading to its electronic asymmetry. A Pd (II) …
different σ-and π-bonding characteristics leading to its electronic asymmetry. A Pd (II) …
Comprehensive Study on Solomonamides: Total Synthesis, Stereochemical Revision, and SAR Studies toward Identification of Simplified Lead
Solomonamides, a pair of macrocyclic peptide natural products originating from marine
sources, have garnered significant attention within the synthetic community owing to their …
sources, have garnered significant attention within the synthetic community owing to their …
Total synthesis: the structural confirmation of natural products
This feature article highlights total synthesis as one of the reliable tools for the structural
confirmation of natural products. Even though there has been substantial improvement in …
confirmation of natural products. Even though there has been substantial improvement in …
Recent achievements in total synthesis for integral structural revisions of marine natural products
MW Ha, J Kim, SM Paek - Marine Drugs, 2022 - mdpi.com
A great effort to discover new therapeutic ingredients is often initiated through the discovery
of the existence of novel marine natural products. Since substances produced by the marine …
of the existence of novel marine natural products. Since substances produced by the marine …
Total Synthesis and Absolute Configuration Determination of the α-Glycosidase Inhibitor (3 S, 4 R)-6-Acetyl-3-hydroxy-2, 2-dimethylchroman-4-yl (Z)-2-Methylbut-2 …
Herein, we report the first total synthesis of α-glycosidase inhibitor (3 R, 4 S)-6-acetyl-3-
hydroxy-2, 2-dimethylchroman-4-yl (Z)-2-methylbut-2-enoate as well as its enantiomer. Our …
hydroxy-2, 2-dimethylchroman-4-yl (Z)-2-methylbut-2-enoate as well as its enantiomer. Our …