Culturing the human microbiota and culturomics

JC Lagier, G Dubourg, M Million, F Cadoret… - Nature Reviews …, 2018 - nature.com
The gut microbiota has an important role in the maintenance of human health and in disease
pathogenesis. This importance was realized through the advent of omics technologies and …

Shotgun metagenomics, from sampling to analysis

C Quince, AW Walker, JT Simpson, NJ Loman… - Nature …, 2017 - nature.com
Diverse microbial communities of bacteria, archaea, viruses and single-celled eukaryotes
have crucial roles in the environment and in human health. However, microbes are …

Unambiguous identification of fungi: where do we stand and how accurate and precise is fungal DNA barcoding?

R Lücking, MC Aime, B Robbertse, AN Miller… - IMA fungus, 2020 - Springer
True fungi (Fungi) and fungus-like organisms (eg Mycetozoa, Oomycota) constitute the
second largest group of organisms based on global richness estimates, with around 3 …

Breast milk-derived human milk oligosaccharides promote Bifidobacterium interactions within a single ecosystem

MAE Lawson, IJ O'Neill, M Kujawska… - The ISME …, 2020 - academic.oup.com
Diet-microbe interactions play an important role in modulating the early-life microbiota, with
Bifidobacterium strains and species dominating the gut of breast-fed infants. Here, we …

MEGAN community edition-interactive exploration and analysis of large-scale microbiome sequencing data

DH Huson, S Beier, I Flade, A Górska… - PLoS computational …, 2016 - journals.plos.org
There is increasing interest in employing shotgun sequencing, rather than amplicon
sequencing, to analyze microbiome samples. Typical projects may involve hundreds of …

Complete nitrification by Nitrospira bacteria

H Daims, EV Lebedeva, P Pjevac, P Han, C Herbold… - Nature, 2015 - nature.com
Nitrification, the oxidation of ammonia via nitrite to nitrate, has always been considered to be
a two-step process catalysed by chemolithoautotrophic microorganisms oxidizing either …

[HTML][HTML] Gut microbial metabolite TMAO enhances platelet hyperreactivity and thrombosis risk

W Zhu, JC Gregory, E Org, JA Buffa, N Gupta, Z Wang… - Cell, 2016 - cell.com
Normal platelet function is critical to blood hemostasis and maintenance of a closed
circulatory system. Heightened platelet reactivity, however, is associated with …

Complete nitrification by a single microorganism

MAHJ Van Kessel, DR Speth, M Albertsen, PH Nielsen… - Nature, 2015 - nature.com
Nitrification is a two-step process where ammonia is first oxidized to nitrite by ammonia-
oxidizing bacteria and/or archaea, and subsequently to nitrate by nitrite-oxidizing bacteria …

MetaPhlAn2 for enhanced metagenomic taxonomic profiling

DT Truong, EA Franzosa, TL Tickle, M Scholz… - Nature …, 2015 - nature.com
To the Editor: MetaPhlAn (metagenomic phylogenetic analysis) 1 is a method for
characterizing the taxonomic profiles of whole-metagenome shotgun (WMS) samples that …

Characterization of the gut microbiome using 16S or shotgun metagenomics

J Jovel, J Patterson, W Wang, N Hotte… - Frontiers in …, 2016 - frontiersin.org
The advent of next generation sequencing (NGS) has enabled investigations of the gut
microbiome with unprecedented resolution and throughput. This has stimulated the …