[HTML][HTML] Effect of charge on the antimicrobial activity of alpha-helical amphibian antimicrobial peptide

MM Islam, F Asif, SU Zaman, MKH Arnab… - Current Research in …, 2023 - Elsevier
Antibiotic resistance is a severe threat to the world's public health, which has increased the
need to discover novel antibacterial molecules. In this context, an emerging class of …

Pharmacoinformatics-based investigation of bioactive compounds of Rasam (South Indian recipe) against human cancer

AK Kalimuthu, T Panneerselvam, P Pavadai… - Scientific reports, 2021 - nature.com
Spice-rich recipes are referred to as “functional foods” because they include a variety of
bioactive chemicals that have health-promoting properties, in addition to their nutritional …

Secondary structure stabilization of macrocyclic antimicrobial peptides via cross-link swap**

N Nazeer, N Kooner, A Ghimire… - Journal of Medicinal …, 2024 - ACS Publications
Lactam cross-links have been employed to stabilize the helical secondary structure and
enhance the activity and physiological stability of antimicrobial peptides; however …

SCMRSA: a new approach for identifying and Analyzing anti-MRSA peptides using estimated propensity scores of dipeptides

P Charoenkwan, S Kanthawong, N Schaduangrat… - ACS …, 2022 - ACS Publications
Staphylococcus aureus is deemed to be one of the major causes of hospital and community-
acquired infections, especially in methicillin-resistant S. aureus (MRSA) strains. Because …

A frog‐derived antimicrobial peptide as a potential anti‐biofilm agent in combating Staphylococcus aureus skin infection

F Fei, T Wang, Y Jiang, X Chen, C Ma… - Journal of Cellular …, 2023 - Wiley Online Library
Abstract Staphylococcus aureus (S. aureus), one of the most prevalent bacteria found in
atopic dermatitis lesions, can induce ongoing infections and inflammation by …

Designing double-site lipidated peptide amphiphiles as potent antimicrobial biomaterials to combat multidrug-resistant bacteria

Z Lai, H Chen, X Yuan, J Tian, N Dong, X Feng… - Frontiers in …, 2022 - frontiersin.org
Rapidly evolving antimicrobial resistance and extremely slow development of new
antibiotics have resulted in multidrug-resistant bacterial infections that present a serious …

Graph theoretical network analysis, in silico exploration, and validation of bioactive compounds from Cynodon dactylon as potential neuroprotective agents against α …

RR Rajeshkumar, BK Kumar, P Parasuraman… - BioImpacts …, 2022 - pmc.ncbi.nlm.nih.gov
Introduction: Parkinson's disease (PD) is a chronic, devastating neurodegenerative disorder
marked by the death of dopaminergic neurons in the midbrain's substantia nigra pars …

[HTML][HTML] In silico and physico-chemical characterization of cluster formation dynamics in peptide solutions

D Kaynarov, K Marinova, R Marinova, P Petkov… - … and Biophysics Reports, 2024 - Elsevier
Although antimicrobial peptides are considered one of the most promising alternatives to
conventional antibiotics given the alarming increase in bacterial multidrug resistance, many …

[HTML][HTML] Structure and formation mechanism of antimicrobial peptides temporin b-and l-induced tubular membrane protrusion

S Zhang, M Ma, Z Shao, J Zhang, L Fu, X Li… - International Journal of …, 2021 - mdpi.com
Temporins are a family of antimicrobial peptides (AMPs) isolated from frog skin, which are
very short, weakly charged, and highly hydrophobic. They execute bactericidal activities in …

[HTML][HTML] Discovery, development and optimisation of a novel frog antimicrobial peptide with combined mode of action against drug-resistant bacteria

J Wang, J Hu, W Pu, X Chen, C Ma, Y Jiang… - Computational and …, 2024 - Elsevier
Antimicrobial peptides (AMP) have emerged as promising candidates for addressing the
clinical challenges posed by the rapid evolution of antibiotic-resistant microorganisms …