Abstract γδ T cells play uniquely important roles in stress surveillance and immunity for
infections and carcinogenesis. Human γδ T cells recognize and kill transformed cells …

Clinical responses to checkpoint inhibitors used for cancer immunotherapy seemingly
require the presence of αβT cells that recognize tumour neoantigens, and are therefore …

γδ T lymphocytes represent∼ 1% of human peripheral blood mononuclear cells and even
more cells in most tissues of vertebrates. Although they have important anticancer functions …

γδ T cells have recently gained considerable attention as an attractive tool for cancer
adoptive immunotherapy due to their potent anti-tumor activity and unique role in …

Natural killer (NK) cells play a significant role in immune tolerance and immune surveillance.
Killer immunoglobin-like receptors (KIRs), which recognize human leukocyte antigen (HLA) …

The efficacy and specificity of conventional monoclonal antibody (mAb) drugs in the clinic
require further improvement. Currently, the development and application of novel antibody …

T-cell receptor (TCR) γδ cells are perceived as innate-like effector cells with the possibility of
mediating graft-vs.-tumor (GVT) without causing graft-vs.-host disease (GVHD) in the setting …

Allogeneic hematopoietic stem cell transplantation (HSCT) using αβ T-/B-cell–depleted
grafts recently emerged as a transplant strategy and highlighted the potential role of γδ T …

We evaluated the kinetics of immune reconstitution (IR) after allogeneic hematopoietic cell
transplantation (HSCT) and analyzed the clinical effect of IR on posttransplant outcomes …

Abstract γδ T cells in human solid tumors remain poorly defined. Here, we describe
molecular and functional analyses of T-cell receptors (TCR) from tumor-infiltrating γδ T …