Tools and techniques for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)/COVID-19 detection

SH Safiabadi Tali, JJ LeBlanc, Z Sadiq… - Clinical microbiology …, 2021 - journals.asm.org
SUMMARY The coronavirus disease 2019 (COVID-19) pandemic, caused by severe acute
respiratory disease coronavirus 2 (SARS-CoV-2), has led to millions of confirmed cases and …

A comparative review of immunoassays for COVID-19 detection

E Mohit, Z Rostami, H Vahidi - Expert review of clinical immunology, 2021 - Taylor & Francis
Introduction: The gold standard for diagnosis of coronavirus disease 2019 (COVID-19) is
detecting severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) by reverse …

Ultrasensitive lateral-flow assays via plasmonically active antibody-conjugated fluorescent nanoparticles

R Gupta, P Gupta, S Wang, A Melnykov… - Nature Biomedical …, 2023 - nature.com
Lateral-flow assays (LFAs) are rapid and inexpensive, yet they are nearly 1,000-fold less
sensitive than laboratory-based tests. Here we show that plasmonically active antibody …

T cell responses to SARS-CoV-2 infection and vaccination are elevated in B cell deficiency and reduce risk of severe COVID-19

R Zonozi, LC Walters, A Shulkin, V Naranbhai… - Science translational …, 2023 - science.org
Individuals with primary and pharmacologic B cell deficiencies have high rates of severe
disease and mortality from coronavirus disease 2019 (COVID-19), but the immune …

[HTML][HTML] Experience with SARS-CoV-2 BNT162b2 mRNA vaccine in dialysis patients

NB Yanay, S Freiman, M Shapira… - Kidney …, 2021 - kidney-international.org
The first emergency-use authorizations for COVID-19 vaccines were granted by the Food
and Drug Administration in December 2020, and clinical trials for the approval of more …

The SARS-CoV-2 RNA–protein interactome in infected human cells

N Schmidt, CA Lareau, H Keshishian, S Ganskih… - Nature …, 2021 - nature.com
Characterizing the interactions that SARS-CoV-2 viral RNAs make with host cell proteins
during infection can improve our understanding of viral RNA functions and the host innate …

[HTML][HTML] SND1 binds SARS-CoV-2 negative-sense RNA and promotes viral RNA synthesis through NSP9

N Schmidt, S Ganskih, Y Wei, A Gabel, S Zielinski… - Cell, 2023 - cell.com
Regulation of viral RNA biogenesis is fundamental to productive SARS-CoV-2 infection. To
characterize host RNA-binding proteins (RBPs) involved in this process, we biochemically …

Comparison of four SARS-CoV-2 neutralization assays

L Riepler, A Rössler, A Falch, A Volland, W Borena… - Vaccines, 2020 - mdpi.com
Neutralizing antibodies are a major correlate of protection for many viruses including the
novel coronavirus SARS-CoV-2. Thus, vaccine candidates should potently induce …

A serum-stable RNA aptamer specific for SARS-CoV-2 neutralizes viral entry

J Valero, L Civit, DM Dupont, D Selnihhin… - Proceedings of the …, 2021 - pnas.org
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic has created
an urgent need for new technologies to treat COVID-19. Here we report a 2′-fluoro …

Long-term immune response to SARS-CoV-2 infection among children and adults after mild infection

C Di Chiara, A Cantarutti, P Costenaro… - JAMA network …, 2022 - jamanetwork.com
Importance Understanding the long-term immune response against SARS-CoV-2 infection
in children is crucial to optimize vaccination strategies. Although it is known that SARS-CoV …