[HTML][HTML] Artificial intelligence in regenerative medicine: applications and implications

H Nosrati, M Nosrati - Biomimetics, 2023‏ - mdpi.com
The field of regenerative medicine is constantly advancing and aims to repair, regenerate, or
substitute impaired or unhealthy tissues and organs using cutting-edge approaches such as …

[HTML][HTML] Organs-on-chips technologies–A guide from disease models to opportunities for drug development

AG Monteduro, S Rizzato, G Caragnano… - Biosensors and …, 2023‏ - Elsevier
Current in-vitro 2D cultures and animal models present severe limitations in recapitulating
human physiopathology with striking discrepancies in estimating drug efficacy and side …

Beyond polydimethylsiloxane: alternative materials for fabrication of organ-on-a-chip devices and microphysiological systems

SB Campbell, Q Wu, J Yazbeck, C Liu… - ACS biomaterials …, 2020‏ - ACS Publications
Polydimethylsiloxane (PDMS) is the predominant material used for organ-on-a-chip devices
and microphysiological systems (MPSs) due to its ease-of-use, elasticity, optical …

Advances in organ-on-a-chip materials and devices

BK Nahak, A Mishra, S Preetam… - ACS applied bio …, 2022‏ - ACS Publications
The organ-on-a-chip (OoC) paves a way for biomedical applications ranging from preclinical
to clinical translational precision. The current trends in the in vitro modeling is to reduce the …

Single-step fabrication of liquid gallium nanoparticles via capillary interaction for dynamic structural colours

RR Sahu, AS Ramasamy, S Bhonsle… - Nature …, 2024‏ - nature.com
Incorporating structural coloured materials in flexible and stretchable elastomeric substrates
requires numerous steps that compromise their scalability and economic viability for …

[HTML][HTML] Gut-on-a-chip: Mimicking and monitoring the human intestine

D Marrero, F Pujol-Vila, D Vera, G Gabriel, X Illa… - Biosensors and …, 2021‏ - Elsevier
Over the last few years, the intestine has been extensively studied using in vitro microfluidic
systems, commonly known as gut-on-a-chip (GOC) devices. This interest has been due not …

Organ-on-a-chip technology: a novel approach to investigate cardiovascular diseases

V Paloschi, M Sabater-Lleal… - Cardiovascular …, 2021‏ - academic.oup.com
The development of organs-on-chip (OoC) has revolutionized in vitro cell-culture
experiments by allowing a better mimicry of human physiology and pathophysiology that has …

Integration of extracellular matrices into organ‐on‐chip systems

H Kutluk, EE Bastounis… - Advanced Healthcare …, 2023‏ - Wiley Online Library
The extracellular matrix (ECM) is a complex, dynamic network present within all tissues and
organs that not only acts as a mechanical support and anchorage point but can also direct …

[HTML][HTML] Organ-on-a-chip microengineering for bio-mimicking disease models and revolutionizing drug discovery

T Ahmed - Biosensors and Bioelectronics: X, 2022‏ - Elsevier
The core of the drug research and screening processes is predicting the effect of drugs prior
to human clinical trials. Due to the 2D cell culture and animal models' poor predictability, the …

Recent trends of biomaterials and biosensors for organ-on-chip platforms

IM Gonçalves, RO Rodrigues, AS Moita, T Hori, H Kaji… - Bioprinting, 2022‏ - Elsevier
Abstract Organ-on-chip (OoC) platforms are a new class of advanced microfluidic devices
that have been attracting significant attention for drug development since they can allow a …