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Dysfunction of ABC transporters at the surface of BBB: potential implications in intractable epilepsy and applications of nanotechnology enabled drug delivery
Epilepsy is a chronic neurological disorder affecting 70 million people globally. One of the
fascinating attributes of brain microvasculature is the (BBB), which controls a chain of distinct …
fascinating attributes of brain microvasculature is the (BBB), which controls a chain of distinct …
Machine Learning for epilepsy: a comprehensive exploration of novel EEG and MRI techniques for seizure diagnosis
Purpose This work focuses on automated epileptic seizure diagnosis (ESD) and prediction
(ESP) to clarify the expanding role of machine learning (ML) in epileptic analysis. It outlines …
(ESP) to clarify the expanding role of machine learning (ML) in epileptic analysis. It outlines …
ABCB1 Polymorphisms and Drug‐Resistant Epilepsy in a Tunisian Population
M Chouchi, H Klaa, I Ben-Youssef Turki… - Disease …, 2019 - Wiley Online Library
Background. Epilepsy is one of the most common neurological disorders with about 30%
treatment failure rate. An interindividual variations in efficacy of antiepileptic drugs (AEDs) …
treatment failure rate. An interindividual variations in efficacy of antiepileptic drugs (AEDs) …
Develo** a gene panel for pharmacoresistant epilepsy: a review of epilepsy pharmacogenetics
Evaluating genes involved in the pharmacodynamics and pharmacokinetics of epilepsy
drugs is critical to better understand pharmacoresistant epilepsy. We reviewed the …
drugs is critical to better understand pharmacoresistant epilepsy. We reviewed the …
Bayesian non-homogeneous hidden Markov model with variable selection for investigating drivers of seizure risk cycling
A major issue in the clinical management of epilepsy is the unpredictability of seizures. Yet,
traditional approaches to seizure forecasting and risk assessment in epilepsy rely heavily on …
traditional approaches to seizure forecasting and risk assessment in epilepsy rely heavily on …
Multi‐omic strategies applied to the study of pharmacoresistance in mesial temporal lobe epilepsy
Mesial temporal lobe epilepsy (MTLE) is the most common type of focal epilepsy in adults,
and hippocampal sclerosis (HS) is a frequent histopathological feature in patients with …
and hippocampal sclerosis (HS) is a frequent histopathological feature in patients with …
Biochemical aspects and therapeutic mechanisms of cannabidiol in epilepsy
APA Boleti, BEF Frihling, PS e Silva… - Neuroscience & …, 2022 - Elsevier
Epilepsy is a chronic neurological disease characterized by recurrent epileptic seizures.
Studies have shown the complexity of epileptogenesis and ictogenesis, in which …
Studies have shown the complexity of epileptogenesis and ictogenesis, in which …
Models for predicting treatment efficacy of antiepileptic drugs and prognosis of treatment withdrawal in epilepsy patients
S Yang, B Wang, X Han - Acta Epileptologica, 2021 - Springer
Although antiepileptic drugs (AEDs) are the most effective treatment for epilepsy, 30–40% of
patients with epilepsy would develop drug-refractory epilepsy. An accurate, preliminary …
patients with epilepsy would develop drug-refractory epilepsy. An accurate, preliminary …
Impact of ABCB1 polymorphism on levetiracetam serum concentrations in epileptic Uygur children in China
T Zhao, J Yu, TT Wang, J Feng, WB Zhao… - Therapeutic Drug …, 2020 - journals.lww.com
Background: Interindividual variations in the efficacy of antiseizure medications make
epilepsy treatment challenging. This is due to genetic factors such as gene polymorphisms …
epilepsy treatment challenging. This is due to genetic factors such as gene polymorphisms …
The Anticonvulsant Effect of Hydroethanolic Leaf Extract of Calotropis procera (Ait) R. Br. (Apocynaceae)
A number of currently used drugs have been obtained from medicinal plants which are a
major source of drugs. These drugs are either used in their pure form or modified to a …
major source of drugs. These drugs are either used in their pure form or modified to a …