Significance: The detrimental effects of ionizing radiation (IR) involve a highly orchestrated
series of events that are amplified by endogenous signaling and culminating in oxidative …

The concept of cell signaling in the context of nonenzyme-assisted protein modifications by
reactive electrophilic and oxidative species, broadly known as redox signaling, is a uniquely …

Over the last decade, a dual character of cell response to oxidative stress, eustress versus
distress, has become increasingly recognized. A growing body of evidence indicates that …

Simple Summary Colorectal cancer (CRC) is very common throughout the world. Despite an
improved outcome with the current treatment regimen, a huge number of patients relapse …

Background Reactive oxygen species-mediated cysteine sulfenic acid modification has
emerged as an important regulatory mechanism in cell signaling. The stability of sulfenic …

Highlights•ROS production is strictly regulated and integrated with other signaling networks
in plants.•Calcium has a critical role in ROS signaling and the control of ROS production.• …

Inflammasomes are components of the innate immune response that have recently emerged
as crucial controllers of tissue homeostasis. In particular, the nucleotide-binding domain …

Reactive oxygen species (ROS) are an intricate part of normal cellular physiology. In excess,
however, ROS can damage all three major classes of macromolecules and compromise cell …

Abstract Glyceraldehyde 3-phosphate dehydrogenase (GAPDH) plays a key regulatory
function in glucose oxidation by mediating fluxes through glycolysis or the pentose …

Significance: Over the past several years, oxidative post-translational modifications of
protein cysteines have been recognized for their critical roles in physiology and …